partial or total alopecia of lower eyelashes, scarring alopecia,
characteristic facies, malformed pinnae, extension of scalp hair
onto cheeks; blind fistulae between ear and angle of mouth
Am
J Dis Child 113:405–410, 1967
Tricho-dental dysplasia
JAAD 53:S130–134, 2005
Trichodysplasia with xeroderma
Tricho-oculo-dermo-vertebral syndrome (Alves syndrome) –
dry, sparse, brittle hair, dystrophic nails, plantar keratoderma,
short stature, cataracts
Am J Med Genet 46:313–315, 1993
Tricho-odonto-onychodysplasia syndrome – autosomal
recessive; alopecia of vertex; hair dry, brittle and sparse, curly,
easily plucked, enamel hypoplasia of teeth, nail dystrophy,
supernumery nipples, palmoplantar hyperkeratosis, melanocytic
nevi
Ped Derm 19:226, 2002; Am J Med Genet 15:67–70, 1983
Tricho-odonto onycho-ectodermal dysplasia (linear dermal
hypoplasia) – hypotrichosis, hypodontia, focal linear dermal
hypoplasia of the tip of the nose, irregular hyperpigmentation
of the back, bilateral amastia and athelia, nerve hearing loss
AD 122:1047–1053, 1986
Trichorhinophalangeal syndrome type I – autosomal dominant;
pear-shaped nose, long philtrum, thin upper lip, receding chin,
tubercle of normal skin below the lower lip, distension and
deviation with fusiform swelling of the PIP joints; hip malformation,
brachydactyly, fine brittle slow-growing sparse hair, eyebrows
sparse laterally, dense medially, short stature
AD 137:1429–1434,
2001; JAAD 31:331–336, 1994; Hum Genet 74:188–189, 1986
Trichorhinophalangeal syndrome type II (Langer–Giedion
syndrome) – facies, bulbous nose, and sparse hair as in
TRPS-I – microcephaly, loose, redundant skin, exostoses
Birth Defects 10:147–164, 1974
Trichothiodystrophy syndromes – BIDS, IBIDS, PIBIDS –
brittle hair, premature aging, sexual immaturity with sparse
or absent axillary, pubic and body hair, few vibrissae and otic
hair, sparse or absent eyelashes and eyebrows, ichthyosis,
dysmyelination, bird-like facies, dental caries;
trichothiodystrophy with ichthyosis, urologic malformations,
hypercalciuria and mental and physical retardation
JAAD
52:224–232, 2005; JAAD 44:891–920, 2001; Ped Derm
14:441–445, 1997; JAAD 22:705–717, 1990; Sabina’s
syndrome – brittle hair, impaired intelligence, decreased
fertility/BIDS (short stature)/IBIDS (ichthyosis)/PIBIDS
(photosensitivity)/Marinesco–Sjögren syndrome – cerebellar
ataxia, physical and mental retardation, dysarthria, cataracts,
fine brittle hair; PIBIDS and chronic neutropenia, recurrent
infections, folliculitis, conjunctivitis
Vohwinkel’s syndrome – occasional diffuse or scarring alopecia
Ped Derm 19:226, 2002
Wallenburg syndrome
Werner’s syndrome (pangeria) – graying of temples in teenage
years with progressive alopecia; sparse or absent pubic and
axillary hair
Medicine 45:177–221, 1966
Wiedemann–Rautenstrauch (neonatal progeroid)
syndrome – autosomal recessive, sparse hair, generalized
lipoatrophy, macrocephaly, premature aging, wide
open sutures, aged and triangular face with hypoplasia
of facial bones, persistent fontanelles, prominent scalp veins,
growth retardation, low-set ears, beak-shaped nose, neonatal
teeth, slender limbs, large hands and feet with long fingers,
large penis, pseudohydrocephalus, psychomotor retardation
Ped Derm 22:75–78, 2005; J Med Genet 34:433–437, 1997;
Eur J Pediatr 130:65–70, 1979; Eur J Pediatr
124:101–111, 1977
Woolly hair, alopecia, premature loss of teeth, nail dystrophy,
reticulate acral hyperkeratosis, facial abnormalities
BJD
145:157–161, 2001
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