Schneiderman Prelims Vol-I. qxd

VASCULAR DISORDERS
Angiokeratoma
Cullen’s sign
Granulation tissue, exuberant
Hemangioma
Henoch–Schönlein purpura
Pyogenic granuloma 
Ped Derm 4:341–343, 1987
Umbilical hemorrhage due to ulceration of the umbilical vein
Vasculitis
UMBILICAL NODULES
AD 128:1265–1270, 1992
Basal cell carcinoma 
AD 139:1497–1502, 2003
Bowen’s disease – plaque 
Cutis 42:321–322, 1988
Carcinoid tumor 
AD 114:570–572, 1978
Cholesteatoma
Colonic mucosa implantation 
BJD 90:108, 1974
Condyloma acuminata
Cutis laxa – umbilical hernia 
Ped Derm 18:365–366, 2001
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A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
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DeBarsey syndrome – umbilical hernia 
Ped Derm 18:365–366,
2001
Dermatofibroma
Desmoid tumor
Ehlers–Danlos syndrome type IX – umbilical hernia 
Ped Derm
18:365–366, 2001
Embryologic rests 
AD 123:105–110, 1987
Endometriomas (32% of all umbilical tumors, most common);
cutaneous endometrioma 
AD 112:1435–1436, 1976; JAMA
191:167, 1965
Endosalpingosis – ectopic fallopian tube epithelium; umbilical
nodule 
BJD 151:924–925, 2004; post-operative endosalpingosis
AD 116:909–912, 1980
Epidermal inclusion cyst
Exstropy of the bladder
Fibroepithelial papilloma
Fibrous umbilical polyp – fasciitis-like proliferation; early
childhood; male predominance 
Am J Surg Pathol
25:1438–1442, 2001
Foreign body granuloma 
AD 139:1497–1502, 2003
Granular cell tumor 
Ghatan p.102, 2002, Second Edition
Hemangioma 
Cutis 76:233–235, 2005;
Hernia 
AD 139:1497–1502, 2003
Hidradenitis suppurativa
Incarcerated hernias
Keloid 
AD 139:1497–1502, 2003
Leiomyosarcoma
Lipoma
Melanocytic nevus 
Rook p.1722–1723, 1998, Sixth Edition
Melanoma 
AD 139:1497–1502, 2003
Malignant Langerhans cell tumor – periumbilical red nodule
JAAD 49:527–529, 2003
Menke gene variant – umbilical hernia 
Ped Derm 18:365–366,
2001
Metastases – Sister Mary Joseph nodule 
BJ Surg 76:728–729,
1989; stomach AD 111:1478–1479, 1975; renal cell carcinoma
J Comput Assist Tomogr 22:756–757, 1998; ovarian JAAD
10:610–615, 1984; pancreas Cutis 31:555–558, 1983; uterus Br
J Clin Pract 46:69–70, 1992; leiomyosarcoma AD 120:402–403,
1984; peritoneal mesothelioma Am J Dermatopathol
13:300–303, 1991; BJ Surg 76:728–729, 1989; JAAD
10:610–615, 1984; acute promyelocytic leukemia AD
140:1161–1166, 2004
Mycobacterium tuberculosis – granuloma Ghatan p.101, 2002,
Second Edition
Neurofibroma
Occipital horn syndrome – umbilical hernia 
Ped Derm
18:365–366, 2001
Omphalith (omphalokeratolith) – the inspissated umbilical bolus
AD 103:221, 1971; Cutis 40:144–146
Omphalitis
Omphaloma 
AD 123:105–110, 1987
Omphalomesenteric duct remnants (vitelline duct remnant) –
umbilical mucosal polyp (cherry red nodule); may vary from
simple mucosal protrusion to moderate or complete prolapse of
the duct and herniation fo the ileum to complete prolapse of the
duct and prolapse of the ileum 
Cutis 76:233–235, 2005;
Textbook of Neonatal Dermatology, p.132, 2001; AD
126:1639–1644, 1990; other omphalomesenteric duct remnants
(deep cyst, Meckel’s diverticulum or sinuses with ectopic
gastrointestinal tissue) 
Cutis 62:83–84, 1998; remnant may
persist as open umbilical enteric fistula or patent vitellointestinal
duct connecting the lumen of the small intestine to the umbilicus
Cutis 76:233–235, 2005
Patent urachal duct 
AD 123:105–110, 1987
Periumbilical choristia
Periumbilical perforating pseudoxanthoma elasticum 
JAAD
39:338–344, 1998; AD 132:223–228, 1996; JAAD 26:642–644,
1992; AD 115:300–303, 1979
Persistent vitelline duct and polyp 
AD 123:105–110, 1987
Pilonidal granulomata
Pilonidal sinus of umbilicus 
Cutis 62:83–84, 1998
Polyp of the umbilicus 
Ped Derm 4:341–343, 1987
Pyogenic granuloma 
Cutis 76:233–235, 2005; Ped Derm
4:341–343, 1987
Sarcoma, congenital 
Cutis 76:233–235, 2005;
Schistosomiasis – ectopic cutaneous granuloma – skin-colored
papule, 2–3-mm; group to form mamillated plaques; nodules
develop with overlying dark pigmentation, scale, and ulceration;
periumbilical 
Dermatol Clin 7:291–300, 1989;
BJD 114:597–602, 1986
Seborrheic keratosis 
AD 139:1497–1502, 2003
Squamous cell carcinoma 
AD 139:1497–1502, 2003
Supraumbilical mid-abdominal raphe 
Ped Derm 10:71–76, 1998
Talc granuloma – older individuals 
BJD 83:151–156, 1970
Tanapox infection 
NEJM 350:361–366, 2004
Umbilical granuloma – most common umbilical mass 
Textbook
of Neonatal Dermatology, p.95,132, 2001
Umbilical hair granuloma and/or sinus
Umbilical hernia, ligated 
Cutis 76:233–235, 2005
Umbilicolith
Urachal and vascular abnormalities (patent urachus) (ectopic
transitional epithelium of bladder) – urachal remnants with cyst,
sinus, or fistula 
Textbook of Neonatal Dermatology, p.132, 2001;
Cutis 62:83–84, 1998
Verrucous carcinoma 
AD 141:779–784, 2005
Yolk sac remnant – umbilico-ileal fistula
Malignant tumors (8.4% of all tumors) 
SA Med Jnl Sept 1980,
p.457; Cancer 18:907, 1965
53% Adenocarcinoma
23% Sarcomas
18% Melanomas
3% Squamous cell carcinoma
3% Basal cell carcinoma
Carcinoid 
Mt Sinai J Med 44:257, 1977