Immune determinants of covid-19 disease presentation and severity



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Document Outline

  • Immune determinants of COVID-19 disease presentation and severity
    • COVID-19 disease courses
      • Mild and severe acute COVID-19. 
      • Long COVID. 
      • Multisystem inflammatory syndrome associated with COVID-19. 
    • Viral recognition and innate immune responses
      • Viral entry. 
      • Innate immune responses. 
    • Adaptive immune responses
    • Known immunological differences between high- and low-risk individuals
      • Sex differences. 
      • Age differences. 
      • Immunodeficiencies. 
      • Future directions. 
    • Acknowledgements
    • Fig. 1 Coronavirus recognition and immune response.
    • Fig. 2 Immune-system parameters associated with obesity, aging and severe COVID-19.

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