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Post Doctoral Fellowship in Cytogenetics
Degree awarded by The Tamil Nadu Dr. M.G.R
Medical University
This is a two-year in-service training programme
in a diagnostic
cytogenomics laboratory, which
deals with the identification of chromosomal
abnormalities. Chromosomal abnormalities are an
important cause of genetic disease, and are seen in a
variety of conditions such as mental retardation,
dysmorphism, delayed or abnormal development,
disordered sexual development, recurrent
abortions, infertility, and cancer. Karyotyping is used
for diagnosis,
planning therapy, and determining
prognosis in many cancers, particularly in
hematological malignancies. Cytogenetic analysis is
also an important component of prenatal diagnosis.
The laboratory handles samples from peripheral
blood, bone marrow, amniotic fluid, and solid tissues
such as chorionic villus, products of conception,
tumors, and skin, for conventional cytogenetic as well
as fluorescence in situ hybridization (FISH) analysis.
Cytogenetic testing for chromosome breakage
syndromes is also performed. In addition, there will
be exposure to molecular genomic techniques such as
DNA extraction, polymerase chain reaction (PCR),
microarray analysis, and sequencing methods.
Fellows are actively involved in processing and
analysis. Academic activities
include seminars and
journal presentations. Fellows also handle some
teaching responsibilities.
Upon completion of the course, fellows will be able to
identify normal and abnormal chromosomes,
describe karyotypes according to the international
system for cytogenomic nomenclature (ISCN), and
write comprehensive reports. They will also be able to
process specimens, handle equipment and trouble-
shoot when necessary, so as to run a diagnostic
cytogenetics service efficiently.
Eligibility: MD/DNB Pathology/Anatomy
Duration: 2 years
Post Doctoral Fellowship in Laboratory
Haematology
The Post Doctoral Fellowship in Laboratory
Haematology equips pathologists to provide high
quality patient care services.
As a laboratory that
offers support to a wide variety of clinical services
r a n g i n g f r o m n e o n a t o l o g y t o t r a n s p l a n t
h a e m a t o l o g y , t h e r e a r e e x c e l l e n t t r a i n i n g
opportunities via exposure to a wide spectrum of
clinical disorders and the role of the laboratory in
providing diagnostic services. Besides analysis of
peripheral blood and bone marrow, haemostasis and
relevant practice of transfusion medicine and
Immunogenetics, the candidate also rotates through
other related specialties like anatomic pathology and
molecular haematology.
There is exposure to laboratory management
including quality systems and automation. Besides
routine lab haematology services,
diagnosis and
classification of haematological malignancies based
on peripheral blood and bone marrow studies forms a
significant part of the training which is augmented by
training on immunopheno typing by flow cytometer,
molecular typing and karyotyping. Training
also helps familiarize with tools to characterize
haemoglobinopathies and red cell disorders.
The special haemostasis lab caters to the diagnostic
and therapeutic monitoring of patients with rare and
common coagulation, platelet and thrombotic
disorders. With more than 25000 blood donations a
year and various types of blood components
production, the candidate also has opportunities to
train in donor management as well as rational blood
use based on guidelines. An exit exam is conducted at
the end of two years.
Eligibility: MD / DNB Pathology/ MD Transfusion
Medicine
Duration: 2 years
Post Doctoral Fellowship in
Neuropathology
The Fellowship
Programme in Neuropathology
provides two years of intensive in-service training in
neuropathology. The programme emphasizes the
development of diagnostic skills and the ability to
synthesize clinico-pathological correlations.
Specific objectives for the course are:
1. Development of skills in diagnostic neuro
pathology of surgical cases.
2. Interpretation of lesions by light and immuno
histochemistry.
3.Training in muscle enzyme histochemistry,
immuno histochemistry and molecular diagnostic
techniques.
There is a large volume of neuro surgical specimens,
about 2000 per year. This includes brain and spinal
cord tumours, skeletal muscle biopsies and
peripheral nerve biopsies. Fellows examine all
Prospectus 2022-2023