I n t e r n a L medicine questions Bank

Ans: C (this is the lowest CD4 and highest viral load )

12. 
    HIV is composed of:A single strand of RNA
    
    
    
13. 
    Which of the following is least likely to transmit HIV?
    

1. 
   Semen
   
2. 
   Saliva
   
3. 
   Blood
   
4. 
   CSF
   
5. 
   Transplanted organs
   

Answer: B (saliva_) http://www.cdc.gov/hiv/resources/qa/transmission.htm

19. 
    Which of the following influenza viruses subtypes is expected to cause the (???) pandemic influenza?
    

19. 
    Neuroamindiase projections in the influenza virus act as:
    

1. 
   Receptors for entry into cells
   
2. 
   Ezymatic function to release the building virus for the cell
   
3. 
   Both A + B
   
4. 
   Cherokinase receptors
   
5. 
   Receptors for IL-1
   

The enzyme helps viruses to be released from a host cell. Influenza virus membranes contain twoglycoproteins: hemagglutinin and neuraminidase. While the hemagglutinin on the surface of the virion is needed for infection, its presence inhibits release of the particle after budding. Viral neuraminidase cleaves terminal neuraminic acid (also called sialic acid) residues
from glycan structures on the surface of the infected cell. This promotes the release of progeny viruses and the spread of the virus from the host cell to uninfected surrounding cells.
Neuraminidase also cleaves sialic acid residues from viral proteins, preventing aggregation of viruses.

19. 
    Which of the following is true regarding brucella:
    

1. 
   monotherapy is the standard of care
   
2. 
   Usually is treated for 3 weeks.  For 6 weeks
   
3. 
   Intracellular activity is important in the antibiotic (choice) for brucellosis
   
4. 
   It is a Gram +ve coci  G-ve bacilli
   
5. 
   Penumonia is a frequent complication  Pneumoniitis is a less common complication
   

19. 
    Which of the following is the closest measurement of core body temperature:
    

1. 
   Oral temperature
   
2. 
   Axillary temperature
   
3. 
   Rectal temperature
   
4. 
   Ear temperature
   
5. 
   Mixed venous temperature
   
   
   

19. 
    Which of the following is false about acute HIV disease?
    

1. 
   It occur within 2-6 weeks of infection
   
2. 
   It is best diagnosed by ELISA  Wrong (However, the standard third generation enzyme linked immunosorbent assays (ELISAs) used in clinical practice and in blood banks in the United States do not detect antibodies to HIV until three to seven weeks after infection.)
   
3. 
   It manifess aa flue-like illness Yes
   
4. 
   It is associated with high infectoiu state → Patients with primary HIV infection are highly contagious to others,
   
5. 
   It occurs in about 70% of patients
   

19. 
    Which of the following is true about S. aureus?
    

1. 
   It lacks a coagulase enzyme
   
2. 
   It rarely causes a nosocomial infection
   
3. 
   It is a gram negative bacili
   

It is associated with infections in patiens with burns  Correct  Burns provide a suitable site for bacterial multiplication and are more persistent richer sources of infection than surgical wounds. Staphylococcus aureus is one of the most frequently isolated pathogens in both community and hospital practices. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3511900/

4. 
   So far, there is no documented resistance to vaoncomycin
   

19. 
    Which fo the following is true about fever of unknown origin?
    

In developing countries, infections contribute to majority of cases.

19. 
    A 70-year-old man with 3 months headache, stiffness, low grade fever, jaw claudication, and amuresiss fugax, his ESR is 100, all of the following statements are true regarding this condition, except:
    

1. 
   Increased risk of permenant blindness
   
2. 
   Tongue claudicaiton
   
3. 
   Weight loss
   
4.