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MU-MCQs-Internal-medicine (2022)

Amyloidosis: types
AL amyloid

      • L for immunoglobulin Light chain fragment

      • due to myeloma, Waldenstrom's, MGUS

      • features include: cardiac and neurological involvement, macroglossia, periorbital eccymoses

AA amyloid





Beta-2 microglobulin amyloidosis



1 0-Which one of the following types of glomerulonephritis is most characteristically associated with Goodpasture's syndrome?



A.

Diffuse proliferative glomerulonephritis





B.

Mesangiocapillary glomerulonephritis




C.

Membranous glomerulonephritis





D.

Rapidly progressive glomerulonephritis


E.

Focal segmental glomerulosclerosis

Goodpasture's syndrome is rare condition associated with both pulmonary haemorrhage and rapidly progressive glomerulonephritis. It is caused by anti-glomerular basement membrane (anti-GBM) antibodies against type IV collagen



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