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Is NaOCl equally effective in dissolving vital, non-vital, or fixed tissue ???



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Is NaOCl equally effective in dissolving vital, non-vital, or fixed tissue ???

  • Demonstrated that 5.25% sodium hypochlorite dissolves vital tissue. (Rosenfeld et al. 1978 )
  • As a necrotic tissue solvent, 5.25% sodium hypochlorite was found to be significantly better than 2.6%, 1%, or 0.5%. (Hand et al.1978)
  • 3% sodium hypochlorite was found to be optimal for dissolving tissue fixed with parachlorophenol or formaldehyde (Thé SD.1979)

NaOCl & Other Medicaments

  • The antibacterial efficacy of sodium hypochlorite, is increased when it is used in combination with other solutions, such as calcium hydroxide, EDTAC, or chlorhexidine.
  • Possibly,the bactericidal effect gained by combining sodium hypochlorite with other chemicals comes from the release of chlorine gas.

NaOCl & Other Medicaments

NaOCl & Ca(OH)2

  • Pretreatment of tissue with calcium hydroxide can enhance the tissue-dissolving effect of sodium hypochlorite.
  • Hasselgren et al.(1988)
  • Combination of calcium hydroxide and sodium hypochlorite was more effective on the dissolution of soft tissue on the root canal wall than using either medicament alone.
  • Wadachi et al.(1998)

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