Irrigation

In Vivo-the antibacterial effect of H2O2

• Bacteria counts were greatly reduced when 10% H2O2 was used as part of the irrigating protocol., but the protocol used could not predictably produce sterile root canals in monkey teeth.

• Möller et al. (2004)

The antibacterial effect of H2O2

• A combination of NaOCl and H2O2 was no more effective against E. faecalis in contaminated root canals than NaOCl alone.
• Siqueira et al. (1997)

H2O2

• Although H2O2 has long been used in disinfection and canal irrigation in endodontics, the available literature does not support its use over that of other irrigating solutions.

MTAD

MTAD

• A mixture of tetracycline isomer, acid, and detergent.
• (doxycycline, citric acid, and the detergent Tween-80)
• It has antibacterial activity.
• It has low pH 2.15