Экономика и социум



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EVALUATION OF THE EFFECTIVENESS OF MODERN METHODS OF TREATMENT OF PARANOID TYPE OF SCHIZOPHRENIA

________________________________________________________________ 
"Экономика и социум" №1(92) 2022 www.iupr.ru
признаки могут наблюдаться в течение длительного времени до первого 
приступа, 
но 
их 
необходимо 
своевременно 
распознать 
и 
классифицировать. Сама шизофрения появляется без каких-либо внешних 
на то причин – считается, что большую роль в данном случае играет 
наследственный фактор.
Ключевые слова: 
параноидная шизофрения, антипсихотическая 
терапия. 
Introduction. 
Most modern standards for the treatment of schizophrenia 
are based on the idea that all antipsychotics are equally effective (with the 
exception of clozapine) and that they differ only in the spectrum of side effects 
[2,5]. Therefore, as drugs of choice it is proposed to use atypical antipsychotics 
of the new generation, which rarely cause neurological disorders [1,3]. 
Traditional antipsychotics are considered as second-line agents due to the 
frequent occurrence of movement disorders and a pronounced inhibitory effect. 
It is indicated that clozapine should only be used as a last resort (reserve drug) 
due to the potential for serious complications. Changing the neuroleptic is 
usually recommended when the previous therapy has failed. 
It is assumed that during the transition to treatment with traditional drugs, 
the effectiveness of which is comparable to atypical antipsychotics, the 
improvement in the condition may be associated with a higher individual 
sensitivity of some patients to drugs in this group. The powerful antipsychotic 
effect of clozapine makes its use useful when other antipsychotics are 
ineffective in 30-60% of patients. 
Despite the attractiveness of the idea underlying the proposed approach 
(high efficiency and good tolerance), the presented differentiated scheme of 
schizophrenia therapy has a number of disadvantages. They are associated with 
the "controversy" of some theoretical data that became the basis for its 
development, and with certain difficulties in its application in clinical practice. 
For example, in recent years, an opinion has been increasingly expressed about 



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