Table 1.
Demographics, previous surgeries
Group A
n= 12
Group B
n= 6
Group C
n= 10
Age (mean)
46,83
52,83
51,90
Menopausal status
Premenopausal
Postmenopausal with HRT
Postmenopausal without HRT
3
6
3
0
2
4
2
1
7
Prior hysterectomy
or urogyne-cologic
or pelvic surgery
0
0
10
Parity
1
2
3
5
6
1
1
5
0
2
6
2
Preoperative prolapse POPQ
Stage I
Stage II
Stage III
0
9
3
0
4
2
4
6
0
Urinary incontinence
Stress
2
0
0
Descriptive statistics of measurable variables are shown in
Table 2 and 3. Mean patient’s age was 49,93 years old, mean
operation time 55,18 minutes (min) and mean estimated blood
loss 118,04 milliliters (mL).
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Laparoscopic colpopexy technique…
Table 2.
Descriptive statistics of measurable variables (age, mean operation time and estimated blood loss)
Mean
SD
Minimum
Maximum
N
Age
49,93
4,19
42,00
58,00
28,00
A (for LSH)
46.83
2.75
42,00
51,00
12,00
B (for TLH)
52,83
1,83
51,00
55,00
6
C (for after_hyster)
51,90
4,33
45,00
58,00
10
mean operation time (min)
55,18
7,63
48,00
70,00
28,00
A (for LSH)
51,50
2.96
48,00
57,00
12,00
B (for TLH)
68,83
1,32
67,00
70,00
6
C (for after_hyster)
51,40
2,17
49,00
55,00
10
mean estimated blood loss (mL)
118,04
22,66
85,00
160,00
28,00
A (for LSH)
120,00
12,06
100,00
140,00
12,00
B (for TLH)
144,16
15,62
120,00
160,00
6
C (for after_hyster)
100,00
20,13
85,00
159,00
10
mean length of hospital stay
3,10
0,46
2,45
3,29
28
A (for LSH)
2.16
0,38
2,00
3,00
12
B (for TLH)
3.33
0,51
3,00
4,00
6
C (for after_hyster)
3.20
0,42
3,00
4,00
10
Table 3.
Descriptive statistics of variables eg. “Operation type”, “POPQ”, “Diagnosis”, “pain at the level of fascia after 1 week”,
“Parity”
Value
Frequency
Percent of Total
Operation type*
A (LSH)
12
42,86
B (TLH)
6
21,43
C (after_hyster)
10
35,71
POPQ**
3
5
17,86
2
19
67,86
1
4
14,29
Diagnosis***
0
10
35,71
1
9
32,14
2
9
32,14
pain at the level of fascia after 1 week****
0
22
78,57
1
6
21,43
Parity (number of deliveries)*****
1
8
28,57
2
17
60,71
3
3
10,71
* Operation type: LSH – laparoscopic subtotal hysterectomy; TLH – total laparoscopic hysterectomy; after hysterectomy
** POPQ (pelvic organ prolaps quantiication): 1 stage; 2 stage; 3 stage
*** Diagnosis: 0 – prolapsus; 1 – Mayoma; 2 – abnormal bleeding
**** Pain at the level of fascia after 1 week: 1 – pain; 0 – without pain
***** Parity: 1 – once, 2 – twice; 3 – for three times delivered
47
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Laparoscopic colpopexy technique…
The Pearson Chi-Square Test was used for assessing de-
pendences in contingency tables between particular immeasur-
able variables (Table 4).
Table 4.
P-values calculated on the basis of the Pearson
Chi-Square Test
Partity
Pain at the
level of facia
after 1 month
Diagnosis POPQ
Operation type
0.475
0.912
0.001
0.035
Partity
-
0.124
0.687
0.065
Pain at the level of
fascia after 1 week
-
-
0.999
0.505
Diagnosis
-
-
-
0.085
Details for variables with statistical signiicance:
Table 4a.
Operation type – Diagnosis
Operation type
diagnosis
Total
%
0
1
2
LSH
0
0.00
8
28.57
4
14.29
12
42.86
TLH
0
0.00
1
3.57
5
17.86
6
21.43
after_hyster
10
35.71
0
0.00
0
0.00
10
35.71
Total
10
35.71
9
32.14
9
32.14
28
100.00
There were found statistical signiicant dependences between
“Operation type” and “Diagnosis” (p=.001, α=.05) and “Opera
-
tion type” and POPQ (p=.035, α=.05). Diagnosis of prolapsus
indicated LSH procedure in 28,57% cases, vs abnormal vaginal
bleeding for TLH in 17,86% (Table 4a).
Table 4b.
Operation type – POPQ
Operation type
POPQ
Total
%
1
2
3
LSH
0
0.00
9
32.14
3
10.71
12
42.86
TLH
0
0.00
4
14.29
2
7.14
6
21.43
after_hyster
4
14.29
6
21.43
0
0.00
10
35.71
Total
%
4
14.29
19
67.86
5
17.86
28
100.00
POPQ 2 indicated LSH procedure in 32,14%, vs 14,29% for
TLH and 21,43% after hysterectomy (Table 4b).
Table 5.
P-values calculated on the basis of the Kruskal-Walis Test
Age*
Mean operation
time*
Mean length of
hospital stay*
Mean estimated
blood loss*
POPQ
0.34
0.56
0.67
0.13
Pain at the level of fascia after1 week
0.48
0.34
1
0.29
Diagnosis
0.0028
0.0111
0.0047
0.046
Parity
0.83
0.58
0.39
0.32
Operation type
0.0017
0.0008
0.001
0.0007
* variable does not follow a speciied theoretical – normal distribution
Statistical signiicance among mean values of quantitative
variables as: “age” (p=.0017, α=.05), and qualitative – “Operation
type” variable is observed (Table 5). It suggests that the age and
the operation type are correlated and mean age for LSH was
46,83, vs TLH 52,83, vs after hysterectomy 51,90.
Mean operation time (p=.0008, α=.05) depended from opera
-
tion type (mean time for all operations was 55,18 min vs 51,50
for LSH vs 68,83 min for TLH and 51,40 for after hysterectomy).
We found statistically signiicant correlation between operation
type and mean length of hospital stay (p=.001, α=.05), for LSH it
was 2,16 days vs 3,33 for TLH and for 3,20 after hysterectomy.
Mean estimated blood loss (p=.0007, α=.05) and operation type
were statistically signiicant, with mean value for LSH 120 mL vs
144,16 mL for TLH and 100 mL for after hysterectomy (Table 5).
Discussion
As with all of the other apical support procedures, it is dificult to
quantify the success rates because of wide variation in outcome
measures and deinitions used for success.
Some studies focus on support of the vaginal apex, while
others consider overall vaginal support. This is more complicated
for abdominal repairs, in which posterior vaginal wall support pro-
cedures are often deferred, and there is a variation in concomitant
procedures for anterior wall support and urinary incontinence.
Most of the studies use synthetic mesh grafts, which offer
durable repairs. Several characteristics of synthetic meshes
appear to affect the prevalence of erosion, including pore size,
ilament type, and weave. The monoilament, macroporous soft
meshes (polypropylene) seem to be the best for use in colpopexy.
A recent randomized control trial provides level I evidence that
allogenic fascia lata is inferior to synthetic mesh (68% versus
91% respectively at 1 year) for sacral colpopexy [10].
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48
Laparoscopic colpopexy technique…
Sacral colpoperineopexy is a modiication of sacral colpo
-
pexy aimed at correcting a combination of conditions, includ-
ing apical prolapsed, rectocele, and perineal descent. During
ascral colpoperineopexy, a continuous graft is placed from the
anterior longitudinal ligament to the perineal body. This can be
accomplished either through a total abdominal approach or
a combined abdominal and vaginal procedure. Cundiff et al.
displayed good anatomical support of the vaginal apex, poste-
rior wall, and perineum over short-term follow-up for 19 women
undergoing sacral colpoperineopexy [11]. Defecatory dysfunction
symptoms completely resolved in 66% of patients. Sullivan et
al reported outcomes for a slightly different variation of sacral
colpoperineopexy involving attachment of Marlex mesh to the
perineal body using a needle carrier [12]. The failure rate was
25% and the mesh erosion rate was 5% for 205 patients with
up to 10-year follow-up.
Colombo and Milani performed a retrospective case-control
study using 62 cases of sacrospinous ligament ixation and 62
matched controls undergoing modiied McCall culdoplasty [13].
There was no statistically signiicant differences in postopera
-
tive objective support, even for women with procidentia. The
authors concluded that McCall culdoplasty was equally efica
-
cious as sacrospinous ligament suspension with less morbidity,
and sacrospinous suspension should no longer be considered
as a treatment in patients with uterovaginal prolapsed.
Laparoscopic sacral colpopexy is an attempt to make sacral
colpopexy less invasive with a quicker recovery, similar to vaginal
surgery. Complication rates, operative time, duration of hospital
-
ization, recovery time, postoperative recovery, and costs have
not been prospectively compared for laparoscopic and open
sacral colpopexy.
There is no available literature for laparoscopic colpopexy
modiication described in the article. This technique, as a whole,
allows a complete anatomical repositioning of the pelvic organs
that inluence their various functions and prevent any possible
new prolapsed.
Laparoscopy is a viable approach for the surgical treatment
of urogenital prolapse. It is a minimally invasive surgery that
requires a short hospital stay. Few complications were observed.
Laparoscopic colpopexy with the addition of mesh is particularly
indicated for women with vaginal vault prolapse who would like
to improve their quality of life. This unique approach can be used
concomitantly with LSH or TLH. It is also helpful for patients
with a history of hysterectomy, for whom laparoscopy will allow
minimal postoperative pain and shorter hospital stay.
The obvious weaknesses of our report include the small
patient number and the short-term follow-up.
Conclusion
The large number of corrective surgical techniques described in
the literature for genitor-urinary prolapsed only proves that there
is still no consensus on this issue.
We believe that the positive results of this minimally invasive
procedure could be ascribed to the use of the typical laparoscopy
technique. It must, however, be performed by an experienced
surgeon.
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The authors have no commercial, property, or inancial inter
-
est in the products or companies described in this article.
Corresponding author: Klaudia Stangel-Wójcikiewicz MD,
PhD, Gynecology and Oncology Department, Collegium Medicum
Jagiellonian University, Kopernika 23, 31-051 Kraków, Poland
E-mail: ksw@cm-uj.krakow.pl
T
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BIO-ALGORITHMS AND MED-SYSTEMS
JOURNAL EDITED BY JAGIELLONIAN UNIVERSITY – MEDICAL COLLEGE
Vol. 7, No. 13, 2011, pp. 49-56
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