Dermatovenerologiya va estetik tibbiyot

5
тезисы
immu nologik (ил-2, ил-6, ил-8, ил-10, ФнO-α) 
tahlillari amalga oshirildi. Kombinatsiyalangan davo 
jarayonida dermatologik hayot sifatining ko‘rsatkichi 
(DHSK, (Dermatology life Quality Index, DlQI) ) 
so‘rovnomasidan foydalanib vitiligoning bemorlarning 
hayot sifatiga ta’siri baholandi.
Barcha bemorlar ikki guruhga bo‘lindi. 1-guruh-
dagi (
n
= 30) bemorlarda kombinatsiyalangan davo – 
311 nm qisqa to‘lqinli uVB terapiyasi, standart davo 
va sitostatiklar bilan o‘tkazildi; 2-guruhda (taqqoslash 
guruhi) (
n
= 30), bemorlar faqat 311 nm qisqa to‘lqinli 
fototerapiya va standart davo oldilar. Ikkala guruhdagi 
fototerapiya kursining davomiyligi 20 haftadan ko‘p 
bo‘lmagan.
natijalar
ko‘rsatkich
klinik sog‘ayish sezilarli yaxshilanish yaxshilanish
Kombinatsiyalangan davo (uVB 311 nm + sitostatik) (
n 
= 30)
21 (70 %)
5 (16,7 %)
4 (13,3 %)
uVB – terapiya 311 nm (
n 
= 30)
9 (30 %)
10 (33,3 %)
11 (36,7 %)
Xulosa. 
Vitiligo bilan kasallangan bemorlar kom-
binatsiyalangan davo batijasida nemorlarning 86,7 % 
hollarida klinik sog‘ayish, sezilarli yaxshilanish kuza-
tilgan bo‘lsa, bu ko‘rsatkich standart davo olgan 
bemorlarda 63,3 % ni tashkil etgan.
triggers For Psoriasis, WHat’s neW?
S. LILUASHVILI, T. KITUASHVILI, G. GALDAVA
«Kanveni – S/R national center of dermatology and venereology», Tbilisi, Georgia
recent studies confirm, that there are changes 
in the understanding of pathogenesis of psoriasis. 
Immune and genetic theories are mainly discussed. 
Triggers play a big role in the onset and exacerbation 
of the disease. The list of triggers varies by different 
authors. They include: Injury (Koebner phenomenon), 
Sunburn, bacterial and viral infections, Drugs 
(Systemic steroids, antibiotics, antiviral medications 
etc.), emotional stress, alcohol consumption, tobacco 
smoking, obesity etc. according to previous studies 
in Georgia, main triggers for psoriasis were alcohol 
and systemic steroids. aim of our study was to 
identify triggers for psoriasis in pandemic conditions.
We have studied 82 patients with severe psoriasis 
vulgari
s
, who were registered at our clinic and 
applied to us due to exacerbation of the disease 
during the pandemic (2020 y). methods of clinical 
evaluations were PaSI (Psoriasis area and Severity 
Indexч, PGa (Physician’s Global assessment) and 
DlQI (Dermatology life Quality index). For patients 
was also developed a questionnaire, which included 
all possible triggers for psoriasis.
The results of the study were distributed as 
follows: The most common triggers are systemic 
steroids (41 %), from here for the treatment of 
COVID-19 infection – 37 %, prescribed by a doctor 
for the treatment of psoriasis – 12 %, used by the 
patient himself – 43 %, for the treatment of other 
disorders – 8 %.
The second main reasons were Emotional stress 
and anxiety disorders (31 %), from here regarding 
pandemic situation – 47 %, as a complication after 
COVID-19 infection – 33 %, other stressful events – 
20 %.
Other triggers were: use of antibiotics (15 %), 
from here during COVID-19 infection treatment for 
concomitant pneumonia – 75 %, for other disorders – 
25.
Other triggers (alcohol, tobacco, obesity etc) – 
13 %.
In conclusion, COVID-19 pandemics has strong 
affect on the ongoing and management of the 
psoriasis.