Dermatovenerologiya va estetik tibbiyot

skin maniFestation oF Hiv inFeCtion in CHilDren
D.D. NABIYEVA
Tashkent pediatric medical institute Tashkent, Uzbekistan
HIV infection due to the diversity of the clinical 
picture, difficulty in diagnosis and treatment is 
becoming serious problem among the population. 
about 2 million people become infected with HIV 
each year in the world and children are not the 
exception.
HIV continues to be a major global public health 
issue, having claimed 36,3 million (27,2–47,8 million) 
lives so far.
There is no cure for HIV infection. However, 
with increasing access to effective HIV prevention, 
diagnosis, treatment and care, including for 

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Дерматовенерология и эстетическая меДицина № 3 / 2021
opportunistic infections, HIV infection has become 
a manageable chronic health condition, enabling 
people living with HIV to lead long and healthy lives.
The most common indicators of HIV infection are 
HIV-associated skin diseases. according to official 
statistics, over 28,000 people with HIV infection are 
registered in the republic of uzbekistan.
Purpose of the study.
To study the common 
dermatoses in HIV-positive children in the republic 
of uzbekistan.
materials and methods.
There were 26 children 
with confirmed HIV infection with skin manifestations 
under the observation. The age of patients at 
the time of the study ranged from 3 to 17 years 
(average 8,4 years). all patients underwent a detailed 
immunogram of peripheral blood and antiretroviral 
therapy was prescribed.
results.
In 12 patients (46,1 %) were diagnosed 
candidiasis of the skin and mucous membranes, 
in 6 patients (23,1 %) – warts and molluscum 
contagiosum, in 3 patients (11,5 %) – atopic 
dermatitis, 5 patients (19,2 %) – pyoderma. The 
clinical efficacy of antiretroviral therapy was asses-
sed by the level of CD4 + and IrI. an immu nological 
study showed a direct correlation between a low 
level of CD4 + and the severity of skin lesions. Skin 
lesions associated with HIV infection are very 
common in children, which indicates the importance 
of a thorough and targeted examination of patients, 
especially those at risk, often suffering from viral, 
fungal and bacterial diseases and having resistance 
to the therapy.