Conference proceedings

MICROBIAL CHARACTERISTICS OF POST-TRAUMATIC 
OSTEOMYELITIS 
OBJECTIVE:
The one of the most important issues in traumatology is prevention and treatment of purulent-septic 
complications of traumatic diseases.
The aim of our study was to establish correlations between osteomyelitis caused by bacterial flora and 
immunological factors. 
METHODS:
On the basis of a comprehensive study of bacteriological and immunological data in 100 patients with various 
etiologies osteomyelitis, using correlation analysis was determined: that the types of microbial complications following 
trauma and the date of the body's immune system depends on etiological factors. The frequency of microbes is different 
and depends on the localization of the injury and the surgical intervention. 
Results: frequency of the etiological factors in the contingent we studied, was distributed as follows: S. aureus-
36,9%, S.Epidermidis-52,4, Ps. aeruginosa 27,4%, E. coli- 13,1%, Proteus- 27,4%. Associated infection (or co-infection 
e.g. S. aureus+S. Epidermidis, or St.Epidermidisis+Ps. Aeruginosa and etc) occurred in 22.6% of cases. A significantly 
high correlation coefficient was observed in patients who came to the clinics spontaneously or with delay, as well as with 
the early onset of the infectious process (up to two weeks) and surgical treatment. It also correlates positively with a 
decrease of following immunological parameters: NK, CD4+, CD8+ and CD 19+, the leucocytes phagocytic index is 
reduced and the blast transformation reaction of lymphocytes rate was increased. There is a significant correlation with 
benign outcome of treatment, which indicates that, the patient was sent for outpatient treatment(R=0, 79).