Conference proceedings

LAB-ON-A-CHIP TECHNOLOGIES IN CONTROL AND DIAGNOSIS OF 
VIRAL INFECTIONS 
Rovshan Khalilov
1
, Irada Huseynova
2
, Aziz Eftekhari
1
[0000-0003-0274-4479],
Soodabeh Davaran
1
, Taras 
Kavetskyy
1
, Aygun Nasibova
1
1
Joint Ukraine-Azerbaijan International Research and Education Center of Nanobiotechnology and Functional Nanosystems, 
Drohobych, Ukraine, Baku, Azerbaijan 
[e-mail]
 
2
Institute of Molecular Biology & Biotechnologies, Azerbaijan National Academy of Sciences, 11 Izzat Nabiyev, Baku AZ 1073, 
Azerbaijan
Abstract. 
An urgent need is required for rapid, sensitive and precise detection of viral disease after the last outbreaks. In this 
context, microfluidics or lab-on-a-chip (LOC)systems which encompass a broad range of detection devices have shown promise. The 
conventional diagnostic methods include enzyme-linked immunosorbent assay (ELISA), immunofluorescence and reverse 

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transcription polymerase chain reaction (RT-PCR). However, they have limitations such as low sensitivity, low specificity, and a need 
for bulky equipment. LOCs have successfully overcome some of these restrictions in different diseases diagnosis including viral 
infections. Fabrication of LOC systems as devices that act either individually or detect the virus in samples with the sample to answer 
method are other appealing advantages. 
Keywords: 
Microfluidic, Viral detection, Immunoassays, Nucleic acid, Commercialization, Health care