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Proceedings of Singapore Conference

www.econferenceglobe.com 
101
barcha sharoitlarni yaratish, eng asosiysi aviachipta narxlariga imtiyozlar berishni yo`lga 
qo`yish lozim.
Foydalanilgan adabiyotlar ro`yxati: 
1.
O`zbekiston Respublikasi Prezidentining ―Ikkinchi Jahon urushida fashizm ustidan 
qozonilgan g`alabaga O`zbekiston xalqining qo`shgan munosib hissasiga bag`ishlangan 
kitob albomni nashr etish chora-tadbirlari to`g`risida‖ Farmoyishi. Toshkent. 
―O`zbekiston‖ 2020. 
2.
 
Егоренков Л. И. Введение в технологию туризма. М.: Финансы и статистика. 2009. – 
153с 
3.
―O`zbek tilining izohli lug`ati: 80000dan ortiq so`z va so`z birikmasi. J.V.Shukrona-
H/Tahrir xay`ati:T.Mirzayev (rahbar) va boshq.; O`zR FA Til va adabiyot in-ti. – T.: 
―O`zbekiston milliy ensiklopediyasi‖ Davlat ilmiy nashriyoti, 2008. 407-bet 
4.
O`zbekiston milliy ensiklopediyasi. 11-jild. Qizilqumit- Ho`rmuz. Tahrir xay`ati: 
A.Azizxo`jayev, B.Alimov, M.Aminov va b. T.: ―O`zbekiston milliy ensiklopediyasi‖ 
Davlat ilmiy nashriyoti, 2005. 183-bet 
Internet sahifalar: 
1.
https://ar-da.ru/aktivnyj-otdyh  
2.
 
https://books.google.ru/books?id=04pA60aYlkEC&pg=PA462&dq=словарь+медицинских+
ностальгия&hl=ru&sa=X&ved=0ahUKEwi8keyw4L7kAhXCxIsKHSA5DSIQ6AEIRDAE#
v=onepage&q=ностальгия&f=false,  Психология. Иллюстрированный словарь. — 
ОЛМА Медиа Групп. — С. 238. — 508 с. — ISBN 9785938780934. 
3.
https://psychology.academic.ru/5502/ностальгия 


5th Global Congress on Contemporary Sciences & Advancements 
Hosted from Singapore 
10th May 2021 
www.econferenceglobe.com 
102
CONGENITAL HEART DEFECTS IN CHILDREN AND 
COMORBIDITY 
Akhmedov A.T., 
Navruzova Sh. I. 
Bukhara State Medical Institute, Uzbekistan 
Purpose of the study. Clinical characteristics of congenital heart defects in comorbidity. 
Materials and methods. The study included 133 sick children with congenital heart defects 
(CHD) under the age of 18 years. The control group consisted of 30 healthy peers (16 boys and 14 
girls). The structure of the CHD of the observed group was 77 - "white" (57.9%) and 56 - "blue" 
defects (42.1%): ventricular septal defect (VSD) - 30 (22.5%), Fallot`s tetrads (TOF) -30 (22.5%), 
transposition of great arteries (TGA) -26 (19.5%), atrial septal defect (ASD) -30 (22.5%), patent 
ductus arteriosus(PDA) -11 (8, 4%), pulmonary artery stenosis (PS) -6 (4.6%). Sick children with 
CHD have repeatedly received conservative treatment for the underlying disease and other 
concomitant diseases, such as acute bronchopneumonia, obstructive bronchitis. All sick children 
were routinely prepared for the operation. 
Results and its discussion. All examined patients were born prematurely, 27 patients of them 
weighing up to 2500 grams (20.3%), 106 sick children over 2500 grams (79.7%). In the 
anamnesis, 75 (56.4%) mothers of sick children with CHD had a pathological course of 
pregnancy, which was associated with extragenital (48.0%) and genital (52.0%) diseases. In the 
mothers of the examined sick children with CHD in 44% of cases, TORCh-infection, in particular 
CMV, was established anamnestically. It was established that early formation of foci of chronic 
infections is observed in children with CHD. Thus, in our studies, 77.5% of children, along with 
the underlying disease (CHD), were diagnosed with concomitant diseases: chronic tonsillitis, 
sinusitis, otitis media, urinary tract infection, anemia, dental caries, thyroid hyperplasia, and lag 
in physical and mental development. The clinical manifestations of CHD were varied depending 
on the species. Lagging in physical development was found in 59 sick children with CHD (44.4%). 
Of these, 48 patients with "blue" CHD (81.4% of cases), in whom growth and development were 
delayed against the background of chronic hypoxemia. 
Conclusions. Features of the functioning of the immune system in critical periods of life, cardiac 
hemodynamic disturbances and chronic hypoxemia are the cause of frequent acute respiratory 
infections and the development of an immunodeficiency state. Comorbidity significantly worsens 
the condition of patients with congenital heart disease, reduces the effectiveness of conservative 
therapy for heart failure, and causes a delay in the necessary surgical correction. With age
patients with complex (blue) types of CHD are characterized by the formation of a vicious circle: 
due to the defect and hemodynamic disturbances, hypoxia develops, which contributes to a delay 
in physical development and the development of frequent acute respiratory infections. Frequent 
acute respiratory infections lead to a decrease in immunity and the formation of foci of chronic 
infections, the exacerbation of which is one of the reasons for late surgical correction, resulting in 
a high risk of postoperative complications


5th Global Congress on Contemporary Sciences & Advancements 
Hosted from Singapore 
10th May 2021 

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