Bachelor degree


Gerhard Gross, Thomas Haupi, Grace Almeida-Porada. Stem cell-dependent therapies. Walter De Gruyter Inc., 2013, 410 p



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3. Gerhard Gross, Thomas Haupi, Grace Almeida-Porada. Stem cell-dependent therapies. Walter De Gruyter Inc., 2013, 410 p.






Module designation


Modules of Individual educational direction /traectory (IED)

"Molecular genetics" internship experience


Module level, if applicable

Module of Individual Educational Trajectory 4: "Genetics technology"


Code, if applicable

MGPE 4511

Subtitle, if applicable

not applicable


Courses, if applicable


Course

Credits

"Molecular genetics" internship experience

3







1 lectures + 2 lab / week

Semester(s) in which the module is taught

7 semester

Person responsible for the module

Dr., Prof. Bisenbayev A.K.

Lecturer

Dr., Prof. Bisenbayev A.K., PhD, Assist.Prof. Taipakova S.M.

Language

Kazakh, Russian, English

Relation to curriculum


(State/Social/ Vocational/IET)

IET


Type of teaching, contact Hours


Lecture

Practicum

Seminars

15 hours per semester (1 hour per week)

30 hours per semester (2 hours per week)

-




Workload


Lectures

Guided self-study

Self-study

15 hours per semester (1 hour per week)

8 hours per semester

60 hours per semester (4 hours per week)

Credit points


3 credits= 5 ECTS

Requirements according to

the examination regulations

Awareness of practical working skills in biochemical genetics, methods of genetic analysis, modern scientific methods, used in genetics and molecular biology.

Recommended prerequisites

GMG 2412 General and molecular genetics

Module objectives/intended

learning outcomes



Knowledge


Skills


Competences

Mechanisms of prokaryotic genes expression, mechanisms of eukaryotic genes expression, mechanisms of RNA splicing and editing.


Remember:

Concepts of molecular, genetic, biochemical, and research methods


Understand:

planning and conducting the experiment, processing experimental data.


Modern methods of molecular genetics.


Apply:

Practical skills of enzyme activity determination, plasmid DNA isolation;


Analysis:

resuts of PCR and restriction.



Ability to design experiments and conduct research on molecular genetics with the latest techniques.


Evaluate:

Handle all equipment and materials required for lab work;


Create:

recombinant DNA molecules.



Content


The course will contain the following topics:

"Molecular genetics" internship experience:

1. Subject and tasks of molecular genetics.

2, 3. Mechanisms of prokaryotic genes expression.

4, 5. Mechanisms of eukaryotic genes expression.

6, 7. Mechanisms of RNA splicing and editing.

8, 9. Characteristic and classification of nucleic acid exchange enzymes.

10, 11, 12. Modern methods of molecular genetics.

13. Methods for creation of recombinant DNA molecules.

14. Antisense RNAs.

15. RNA-interference.



Study and examination

requirements and forms of

examination

1st interim control: attendance, in-class discussion, problem solving, testing

2nd interim control: attendance, in-class discussion, problem solving, testing

Final examination: written, 2 theoretical questions, 1 practical question


Media employed

Flash and ppt presentations

Reading list

References (all in English):

1. Bruce Alberts et al. Molecular Biology of the Cell. – Garland Science, 2007, 1392 p.



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