Гигиена, санитария и эпидемиология
ГИГИЕНА, САНИТАРИЯ И ЭПИДЕМИОЛОГИЯ
УДК: 664(082)
РЕЗУЛЬТАТЫ ИЗУЧЕНИЯ ОСТРОЙ ТОКСИЧНОСТИ ПИЩЕВОЙ СМЕСИ “МЕЛЛА КРУАССАН”
Шеркузиева Г.Ф., Хегай Л.Н., Самигова Н.Р., Азизова Ф.Л., Курбанова Ш.И.
“МЕЛЛА КРУАССАН” ОЗУҚА АРАЛАШМАСИНИНГ ЎТКИР ЗАҲАРЛИЛИГИНИ ЎРГАНИШ
НАТИЖАЛАРИ
Шерқўзиева Г.Ф., Хегай Л.Н., Самигова Н.Р., Азизова Ф.Л., Қурбонова Ш.И.
THE RESULTS OF THE STUDY OF ACUTE TOXICITY OF THE FOOD MIXTURE «MELLA
CROISSANT»
Sherkuziev G.F., Khegai L.N., Samigova N.R., Azizova F.L., Kurbanova Sh.I.
Ташкентская медицинская академия
Maqsad: o’tkir zaharlanishni o’rganish va “Mella kroskant” oziq-ovqat aralashmasining intragastral yo’lida
uning sinfini aniqlash. Material va usullar: “Mella kruvasan” oziq-ovqat aralashmasining o’tkir zaharliligi bo’yicha
tajribalar hayvonlarning 2 guruhida o’tkazildi: 1-guruh (eksperimental) – og’irligi 150-165 g bo’lgan 6 ta oq kalamush.
intragastral ravishda 4,71 ml/100 g (doz 5000 mg/kg ga teng). Nazorat vazifasini o’tagan 2-guruhdagi 6 ta hayvonlar
distillangan suv olishdi. Natijalar: intragastral kirib borish paytida o’tkir zaharlanish ko’rsatkichlari bo’yicha “Mella
kroskant” oziq-ovqat qo’shimchasi 4-sinfga kiradi (kam zaharli modda). Xulosa: o’rganilgan oziq-ovqat aralashmasi
teriga mahalliy tirnash xususiyati beruvchi ta’sir ko’rsatmaydi, tavsiya etilgan dozada 413 mg/kg dozada material va
funktsional kumulyatsiya xususiyatlari. Xulosa:
Kalit so’zlar: ovqatlanish, biologik faol qo’shimchalar, toksiklik, oziq-ovqat aralashmasi, qon tarkibi, biokimyoviy
ko’rsatkichlar.
Objective: To study acute toxicity and determine its class in the intragastric route of intake of the food mixture “Mella
croissant” Material and methods: Experiments on the acute toxicity of the food mixture “Mella croissant” were carried
out on 2 groups of animals: group 1 (experimental) – 6 white rats weighing 150-165 g. The prepared suspension of the
food mixture “Mella croissant” was administered once intragastrically at the rate of 4.71 ml/100 g (dose equivalent of
5000 mg/kg). 6 animals of the 2nd group, which served as a control, received distilled water. Results: food supplement
“Mella croissant” according to the parameters of acute toxicity during the intragastric route of entry belongs to class
4 (low toxicity substance). Conclusions: The studied food mixture does not have a local irritant effect on the skin, the
properties of material and functional cumulation in the recommended dose of 413 mg/kg.
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