Webster's New World Medical Dictionary


muscular dystrophy, tibial



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Webster s New World Medical Dictionary (1)

muscular dystrophy, tibial
A form of muscular
dystrophy (MD) in which weakness is usually con-
fined to the anterior compartment (the front part)
of the lower leg and, in particular, to the tibialis
anterior muscle. The weakness usually starts at age
35 to 45, or even much later. Tibial MD is inherited
in an autosomal dominant manner.
mutagen
Something that is capable of mutating
DNA. Among the known mutagens are radiation,
certain chemicals, and some viruses.
mutant
An individual with a mutant (changed)
gene.
mutation
A change in a gene. Mutations can be
caused by many factors, including random chance
and environmental insult. See also 
missense muta-
tion; point mutation.
mute 1
A person who does not speak, either
because of an inability to speak or an unwillingness
to speak. The term is specifically applied to a per-
son who, due to profound congenital or early deaf-
ness, is unable to use articulate language and so is
deaf-mute. 
2
The condition of not speaking. See
also 
apraxia of speech; autism; elective mutism;
selective mutism.
3
In speech, a letter that is
silent, or an element of speech that is formed by a
position of the mouth that stops the passage of the
breath, such as the letters p, b, d, k, and t.
mutism
The inability or unwillingness to speak.
See also 
apraxia of speech; autism; elective
mutism; selective mutism.
mutism, akinetic
A state in which a person is
unable to speak (mute) or move (akinetic).
Akinetic mutism is often due to damage to the
frontal lobes of the brain.
myalgia
Pain in the muscles or within muscle
tissue.
myalgia, epidemic
See 
Bornholm disease.

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