Webster's New World Medical Dictionary

Kartagener syndrome
A genetic syndrome that
is characterized by sinusitis, bronchiectasis (widen-
ing and inflammation of the bronchi), dextrocardia
(heart on the right side of the chest), and infertility.
Kartagener syndrome is inherited in an autosomal
recessive manner. Kartagener syndrome is usually
due to mutation in the gene called DNAI1 on chro-
mosome 9. However, linkage studies have mapped
the disease gene to 5p and 19q in some families,
indicating that Kartagener syndrome is more than
one genetic entity. Also known as ciliary dyskinesia
syndrome.
karyotype
A standard arrangement of the chro-
mosome complement prepared for chromosome
analysis. A normal female karyotype would include
each of the 22 pairs of autosomes (nonsex chromo-
somes), arranged in numeric order, together with
the two X chromosomes.
karyotyping
The preparation, analysis, and
interpretation of a karyotype.
karyotyping, flow
See 
flow karyotyping.
Kawasaki disease
A syndrome that mainly
affects young children, causing fever; reddening of
the eyes (conjunctivitis), lips, and mucous mem-
branes of the mouth; ulcerative gum disease (gin-
givitis); swollen glands in the neck (cervical
lymphadenopathy); and a rash that is raised and
bright red (maculoerythematous). The rash
appears in a “glove-and-sock” fashion over the skin
of the hands and feet. The skin then becomes hard
and swollen (edematous), and it peels off. Kawasaki
disease affects the blood vessels and is now the
main cause of acquired heart disease in children. It
is most common in people of Asian descent, and it is
more common in males than in females. Its cause 
is unknown; current theories include a virus or
other infectious agent. Treatment usually involves
intravenous immunoglobulin (IVIG). Also known 
as mucocutaneous lymph node syndrome, infantile
polyarteritis.