Webster's New World Medical Dictionary


GIFT Gamete intrafallopian transfer. gigantism 1



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Webster s New World Medical Dictionary (1)

GIFT
Gamete intrafallopian transfer.
gigantism 1
Extreme growth in height. Gigantism
is usually associated with disorders of the pituitary
gland, which secretes human growth hormone
(somatotrophin) during childhood, before the
bones fuse.
2
Extreme growth of specific body
parts. See also 
gigantism, focal.
gigantism, eunuchoid
Extremely tall stature
due to the delayed onset of puberty that permits the
continued growth of the long bones before their
growing ends (epiphyses) fuse and growth stops.
gigantism, focal
Extreme growth of specific body
parts, such as one arm, the tongue, or a combination
of parts, as seen in Beckwith-Wiedemann syndrome
or acromegaly. Focal gigantism may occur before or
after the bones fuse. If it occurs afterward, it causes
disfigurement. Surgery for mass reduction can help
improve function, and other treatments may be avail-
able for specific conditions.
gigantism, pituitary
Extreme growth in height
caused by oversecretion of growth hormone (soma-
totrophin) by the anterior pituitary gland. Other fea-
tures of pituitary gigantism include thickening of the
skin, enlargement of the bones, and elongation of
the jaw and other areas. Pituitary gigantism may be
caused by an adenoma of the pituitary gland, a
benign tumor of the pituitary gland, or other causes.
Treatment is usually possible with hormones, sur-
gery, or both. See also 
acromegaly.
Gilbert syndrome
A common but harmless
genetic condition in which UDP-glucuronosyltrans-
ferase, a liver enzyme that is essential to the disposal
of bilirubin, is abnormal. Mutations in the same
gene cause the Crigler-Najjar syndrome, which is a
more severe and dangerous form of hyperbiliru-
binemia (high bilirubin in the blood). Also known
as hyperbilirubinemia type 1.

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