Webster's New World Medical Dictionary

cleidocranial dysostosis
A genetic disorder of
bone development that is characterized by absent or
incompletely formed collarbones and cranial and
facial abnormalities that may include square skull,
late closure of the sutures of the skull, late closure
of the fontanels, low nasal bridge, delayed eruption
of the teeth, and abnormal permanent teeth. A child
with this disorder can bring his or her shoulders
together, or nearly so. The gene for cleidocranial
dysostosis has been found on chromosome 6 in
band p21. Also known as cleidocranial dysplasia
and craniocleidodysostosis.
click-murmur syndrome
See 
mitral valve 
prolapse.
climacteric 1
Menopause in women.
2
The
time corresponding to menopause in the life of
men.
clinical 1
Having to do with the examination and
treatment of patients.
2
Applicable to patients.
The term comes from the French “clinique” (at the
bedside).
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clinical
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clinical cytogenetics
The application of chro-
mosome analysis to clinical medicine. For example,
clinical cytogenetic testing is done to look for an
extra chromosome 21 in a child who is suspected of
having Down syndrome. 
clinical depression
Depressed mood that meets
the DSM-IV criteria for a depressive disorder. The
term clinical depression is commonly used to
describe depression that is a type of mental ill-
ness—not a normal, temporary mood caused by
life events or grieving.
clinical disease
A disease that has recognizable
clinical signs and symptoms, as distinct from a sub-
clinical illness, which lacks detectable signs and
symptoms. Diabetes, for example, can be a subclin-
ical disease for some years before becoming a clin-
ical disease.