Systemic lupus erythematosus and rheumatoid arthritis

15. Paper II: Association of a 
PDCD1
 polymorphism with renal 
 manifestations in systemic lupus erythematosus. 
Comparison of patients and controls failed to reveal an association between 
susceptibility for SLE in individuals from northern Sweden with the 
PD1.3
A 
risk allele (Figure 11).
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Figure 11.
Genotype and allele frequencies of the PD-1.3 polymorphism in patients with SLE and 
population-based controls. Values for the A allele are the frequency, all other values are the 
observed counts (%). 
When stratifying for renal disorder, according to the ACR criteria, there was a 
clear association between the 
PD1.3
A allele and renal disorder with an odds 
ratio of 2.71 (Table 11).
Table 11.
Comparisons of genotype, allele and carrier frequencies between SLE patients 
with and without renal disorder (ACR criterion 7).