Smallpox Presentation



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SmallpoxMonkeypox

Smallpox

  • Variola

Overview

  • Center for Food Security and Public Health Iowa State University - 2004
  • Organism
  • History
  • Epidemiology
  • Transmission
  • Disease in Humans
  • Disease in Animals
  • Prevention and Control

The Organism

The Organism

  • Center for Food Security and Public Health Iowa State University - 2004
  • Double stranded DNA
  • Orthopoxvirus
    • Variola, cowpox, vaccinia, monkeypox,
  • Variola major or minor
  • Stable out side host
    • Retains infectivity
  • Last case, 1977
  • Eradicated, 1980

History

History of Smallpox

  • Center for Food Security and Public Health Iowa State University - 2004
  • First appeared in Northeastern Africa around 10,000 BC
  • Skin lesions on mummies
    • 1570-1085 BC
    • Ramses V

History of Smallpox

  • Center for Food Security and Public Health Iowa State University - 2004

Variolation

  • Center for Food Security and Public Health Iowa State University - 2004
  • Ground scabs, pus, vesicles used to vaccinate
    • China, powdered scabs blown into nostrils
    • India, application of scab or pus to scarified skin
  • Children exposed to mild smallpox

Variolation

  • Center for Food Security and Public Health Iowa State University - 2004

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