Schneiderman Prelims Vol-I. qxd

INFLAMMATORY DISORDERS
Eosinophilic fasciitis – acquired ichthyosis 
JAAD 34:1079–1080,
1996
Sarcoid 
JAAD 40:862–865, 1999; JAAD 17:616–620, 1987;
AD 114:100–101, 1978
METABOLIC
Anorexia nervosa – xerosis; flaky paint scaling 
JAAD 21:1–30,
1989
Biotin deficiency – xerosis; flaky paint scaling
JAAD 15:1263–1274, 1986
Biotinidase deficiency – neonatal and infantile; early resemble
ichthyosiform eruption; both are autosomal recessive; neonatal –
holocarboxylase synthetase deficient; first 6 weeks of life; fiery
red intertriginous dermatitis; infantile – biotinidase deficient;
early, ichthyosiform eruption; after 3 months of life, intertriginous
rash with keratoconjunctivitis, xerosis, generalized pallor,
periorificial dermatitis, alopecia, branny desquamation, and
atrophic glossitis 
Semin Dermatol 10:296–302, 1991;
JAAD 9:97–103, 1983
Celiac disease 
Eur J Dermatol 10:398–399, 2000
Diabetes mellitus – migratory ichthyosiform dermatosis
(polycyclic ichthyosiform rash) with type 2 diabetes mellitus and
insulin resistance 
AD 135:1237–1242, 1999
Essential fatty acid deficiency – xerosis 
JAAD 21:1–30, 1989
Gaucher’s disease, type 2 – autosomal recessive; collodion
baby, mild scaling later 
Curr Prob Derm 14:71–116, 2002;
Arch Dis Child Fetal Neonatal Ed 82:F163–166, 2000;
Arch Dis Child 66:667, 1991; congenital ichthyosis with
restrictive dermopathy 
Obstet Gynecol 81:842–844, 1993
Hemochromatosis – ichthyosis-like atrophic dry skin
AD 113:161–165, 1977; Medicine 34:381–430, 1955
Hyperparathyroidism 
JAAD 40:862–865, 1999;
JAAD 21:801–802, 1989
Hypohidrosis
Ross’ syndrome
Hypopituitarism 
JAAD 40:862–865, 1999
Hypothyroidism (myxedema) 
JAAD 40:862–865, 1999
Kwashiorkor – xerosis; begin as red–purple–brown patches
which heal as flaky paint scaling 
Cutis 67:321–327, 2001;
JAAD 21:1–30, 1989; in elderly, cracked skin on lower abdomen
and pretibial areas (geriatric nutritional eczema) 
Rook p.2662,
1998, Sixth Edition
Liver disease, chronic 
Rook p.2653, 1998, Sixth Edition;
cirrhosis – zinc deficiency; generalized dermatitis of erythema
craquele (crackled and reticulated dermatitis) with perianal and
perigenital erosions and crusts; cheilitis, hair loss 
Rook p.2726,
1998, Sixth Edition; Ann DV 114:39–53, 1987
Malabsorption syndromes 
JAAD 40:862–865, 1999
Malnutrition 
Hautarzt 46:836–840, 1995
Marasmus – xerosis 
JAAD 21:1–30, 1989
Multiple sulfatase deficiency – autosomal recessive; broad
thumbs, mild ichthyosis, gargoylism, mental retardation,
mucopolysacharidosis 
BJD 147:353–355, 2002; Ped Derm
18:388–392, 2001; Ped Derm 14:369–372, 1997
Panhypopituitarism 
BJD 97:327–334, 1977
Pellagra (niacin deficiency) – red pigmented sharply marginated
photodistributed rash, including drug-induced pellagra-like
dermatitis – 6-mercaptopurine, 5-fluorouracil, INH (all of the
above – also seb derm-like); resembles Hartnup disease
Cutis 68:31–34, 2001; JAAD 40:862–865, 1999; Ped Derm
16:95–102, 1999
Phrynoderma (vitamin A deficiency) – xerosis
JAAD 40:862–865, 1999; JAAD 21:1–30, 1989
Renal disease 
JAAD 40:862–865, 1999
Vitamin A excess 
Ghatan p.122, 2002, Second Edition
Zinc deficiency 
JAAD 40:862–865, 1999