Coxsackie A (5,9,10,16) – maculopapular–vesicular
Tyring
p.3,463, 2002; Rook p.998, 1998, Sixth Edition; Coxsackie A4 –
widespread vesicular eruption
Pediatrics 41:873–882, 1968
Cryptococcosis – vesicles and bullae; may simulate herpes
simplex or varicella/zoster virus infection
AD 112:1734–1740,
1976
Cutaneous larva migrans
Cytomegalovirus infection
JAAD 18:1330–1338, 1988; JAAD
12:720–721, 1985; vesiculobullous lesions Dermatology
200:189–195, 2000; JAAD 38:349–351, 1998
Dracunculosis – small papule or vesicle which ruptures
Dermatol Clinic 7:323–330, 1989
Echovirus 4,9,11 – maculopapular–vesicular
Rook p.998, 1998,
Sixth Edition; Echovirus 11 – vesicular rash AD 113:1705–1706,
1977
Ehrlichiosis – human monocytic ehrlichiosis
JAAD 49:363–392,
2003
Enterobacter cloacae JAAD 27:637–638, 1992
Enteroviral infection – vesicular lesions in AIDS
Erysipelas – bullous cellulites; bullous erysipelas
Erythema (chronicum) migrans –
Borrelia burgdorferi; Lyme
disease
Am J Med 99:412–419, 1995
Escherichia coli sepsis – bullous cellulitis
Exanthem subitum with vesicular lesions
BJD 132:614–616, 1995
Fire ant stings (
Solenopsis invicta) – clusters of vesicles evolve
into umbilicated pustules on red swollen base; crusting, heal
with scars; urticaria
J S C Med Assoc 95:231–235, 1999; Ann
Allergy Asthma Immunol 77:87–95, 1996; Allergy 50:535–544,
1995; Ped Derm 9:44–48, 1992
Fire corals – urticarial lesions followed by vesiculobullous rash,
chronic granulomatous and lichenoid lesions
Contact Dermatitis
29:285–286, 1993; Int J Dermatol 30:271–273, 1991
Foot and mouth disease (Echovirus) – adults and children
in direct contact with infected livestock; vesicles of buccal
mucosa, tongue, lips, palms, soles, interdigital skin
Br Med
J 4:529–530, 1967
Fournier’s gangrene
Gas gangrene
Glanders –
Pseudomonas mallei – cellulitis which ulcerates
with purulent foul-smelling discharge, regional lymphatics
become abscesses; nasal and palatal necrosis and destruction;
metastatic papules, pustules, bullae over joints and face, then
ulcerate; deep abscesses with sinus tracts occur; polyarthritis,
meningitis, pneumonia
Rook p.1146–1147, 1998, Sixth Edition
Gonococcemia – periarticular lesions appear in crops with
red macules, papules, vesicles with red halo, pustules, bullae
becoming hemorrhagic and necrotic; suppurative arthritis and
tenosynovitis
Ann Intern Med 102:229–243, 1985
Gram-negative web space infection
Hand, foot, and mouth disease (Coxsackie A5,10,16) –
vesicular and papulovesicular lesions
Rook p.998,1086,
1998, Sixth Edition; BJD 79:309–317, 1967; oral vesicles
Rook p.3057, 1998, Sixth Edition
Herpangina – Coxsackie A1, A6, A10, A22, B1–5, Echovirus
types 9, 11, 17
Prog Med Virol 24:114–157, 1978; oral vesicles
Rook p.3057, 1998, Sixth Edition
Herpes B infection – Macaque monkey bite; herpes simplex-like
lesions with vesicles, erythema, and edema near bite site;
secondary vesiculopapular eruption
JAAD 49:979–1000, 2003;
Tyring p.237–239, 2002; AD 125:1247–1248, 1989
Herpes simplex – primary
Tyring p.75, 2002; neonatal, HIV,
disseminated, eczema herpeticum; palmar and plantar bullae in
infancy
Ped Derm 15:108–111, 1998; AD 114:406, 1978; herpetic
whitlow; dyshidrosis-like herpes simplex in AIDS
JAAD
13:845–852, 1985; eczema herpeticum (Kaposi’s varicelliform
eruption)
Rook p.1028, 1998, Sixth Edition; Arch Dis Child
60:338–343, 1985; oral vesicles Rook p.3057, 1998, Sixth Edition
Herpes zoster
Impetigo, bullous – staphylococcal
Curr Prob Dermatol
5:196–204, 1993; non-bullous (streptococcal) – thin walled
vesicle on red base ruptures and crusts; palmar and plantar
bullae in infancy
Ped Derm 15:108–111, 1998
Infected vascular gangrene
Infectious mononucleosis – vesicular and bullous exanthems
Tyring p.149, 2002
Insect bite reaction – papules with overlying vesicle
Rook
p.1425–1426, 1998, Sixth Edition; bullae in children, associated
with CLL
Acta DV (Stockh) 57:81–92, 1977; natural killer cell
lymphocytosis
AD 126:362–368, 1990; HIV disease JAAD
29:269–272, 1993; fleas, mosquitoes, gnats, midges, flies,
mites, bugs, beetles, thrips (thunder flies);
Haematosiphon
(Mexican chicken bug) – wheals, papules, vesicles, pustules,
crusts
Rook p.1445–1446, 1998, Sixth Edition; ; mites – barley
itch, grain-shoveller’s itch, grain itch, straw itch, cotton seed
dermatitis
Rook p.1468, 1998, Sixth Edition; beetles (Paederus
fuscipes) – blisters, papules Eur J Ped 152:6–8, 1993; bedbugs
(
Cimex lectularis, C. hemipterus) The Clinical Management of
Itching; Parthenon; p.63, 2000; sandflies (Phlebotomus,
Lutzomyia) – harara, urticaria multiformis endemica in Middle
East
The Clinical Management of Itching; Parthenon; p.64, 2000
Jellyfish stings
Leprosy – Lucio’s phenomenon
AD 114:1023–1028, 1978;
erythema nodosum leprosum
JAAD 51:416–426, 2004; AD
132:1432–1434, 1996
Listeria monocytogenes – contact listeriosis; localized vesicles
or pustules
JAAD 48:759, 2003
Lyme disease – vesicular form with secondary necrosis
JAAD
49:363–392, 2003
Marburg virus – maculopapular-vesicular
Rook p.998, 1998,
Sixth Edition
Measles – with extensive bullous eruption
NEJM 277:248–250,
1967
Meningococcemia
Milker’s nodule
Tyring p.57, 2002; vesicopapule JAAD 44:1–14,
2001
Millipede secretions – conjunctivitis and mahogany
pigmentation with bullae
Cutis 67:452, 2001
Mites – cheese mite (
Glyciphagus) bites – papulovesicles and
pustules
Dermatol Clin 8:265–275, 1990
Monkeypox – exanthem indistinguishable from smallpox
(papulovesiculopustular) (vesicles, umbilicated pustules, crusts)
CDC Health Advisory, June 7,2003; JAAD 44:1–14, 2001; J
Infect Dis 156:293–298, 1987
Morganella morgagni JAAD 12:575–576, 1985
Mosquito bite hypersensitivity syndrome in EBV-associated
natural killer cell leukemia/lymphoma – clear or hemorrhagic
bullae with necrosis, ulceration and scar formation
JAAD
45:569–578, 2001
Mucormycosis
Med 64:115–133, 1985
Mycobacterium tuberculosis – miliary tuberculosis; large
crops of blue papules, vesicles, pustules, hemorrhagic
papules; red nodules; vesicles become necrotic to form ulcers
Practitioner 222:390–393, 1979; Am J Med 56:459–505,
1974; AD 99:64–69, 1969
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