Schneiderman Prelims Vol-I. qxd

72
A CLINICIAN
’
S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Schneiderman page 1-100.qxd 5/16/2006 6:49 PM Page 72

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Tricho-odonto-onycho-ectodermal dysplasia (linear dermal
hypoplasia) – hypotrichosis, hypodontia, focal linear dermal
hypoplasia of the tip of the nose, irregular hyperpigmentation
of the back, bilateral amastia and athelia, nerve hearing loss
AD 122:1047–1053, 1986
Trichothiodystrophy syndromes – BIDS, IBIDS, PIBIDS – facial
hemiatrophy, lipoatrophy, sparse or absent eyelashes and
eyebrows, brittle hair, premature aging, sexual immaturity,
ichthyosis, dysmyelination, bird-like facies, dental caries;
trichothiodystrophy with ichthyosis, urologic malformations,
hypercalciuria and mental and physical retardation 
Ped Derm
14:441–445, 1997; JAAD 44:891–920, 2001
Trisomy D (13–15) – membranous aplasia cutis,
holoprosencephaly, seizures, ocular abnormalities,
deafness, neural tube defects 
Textbook of Neonatal
Dermatology, p.127, 2001
Trisomy 13/18 – scalp defects 
BJD 151:953–960, 2004; thin
or atrophic nails 
Ghatan p.109, 2002, Second Edition
Tuberous sclerosis – hypoplasia of the hand 
BJD 135:1–5, 1996
Turner’s syndrome – thinning and wrinkling of palmar skin; thin
or atrophic nails 
Ghatan p.109, 2002, Second Edition
Twenty nail syndrome – atrophic nails 
Ghatan p.114, 2002,
Second Edition
Unusual facies, lipodystrophy, joint contractures (Werner-like
disorder) 
Hum Genet 83:209–216, 1989
Van der Woude syndrome – congenital lower lip pits
Vertebral and eye anomalies, cutis aplasia, and short stature
(VECS) 
Am J Med Genet 77:225–227, 1998
Werner’s syndrome – loss of subcutaneous tissue; bird-like
facies, spindly legs 
Am J Med 108:143–152, 2000; AD
124:90–101, 1988
Wiedemann–Rautenstrauch (neonatal progeroid syndrome) –
generalized lipoatrophy, macrocephaly, premature aging,
wide open sutures, hypoplasia of facial bones, low-set ears,
beak shaped nose, neonatal teeth, slender limbs, large
hands and feet with long fingers, large penis 
J Med Genet
34:433–437, 1997
Williams syndrome – premature laxity of skin, congenital heart
disease (supravalvular aortic stenosis), baggy eyes, full cheeks,
prominent lips, dental malocclusion, delayed motor skills,
cocktail party personality 
J Pediatr 113:318–326, 1988
Wolf–Hirschhorn syndrome (del (4p) syndrome) – midline scalp
defect 
BJD 151:953–960, 2004; Am J Med Genet 21:351–358,
1985
Wrinkly skin syndrome – wrinkled skin on abdomen and dorsal
aspects of hands and feet, increase palmoplantar creases,
prominent venous pattern on chest, mental retardation,
microcephaly, hypotonia, musculoskeletal abnormalities 
Am J
Med Genet 101:213–220, 2001; Ped Derm 16:113–117, 1999
X-p22 microdeletion syndrome – bilateral reticulated and linear
defects of malar region of face, microphthalmia, sclerocornea
Textbook of Neonatal Dermatology, p.127, 2001
Xeroderma pigmentosum 
Ghatan p.5, 2002, Second Edition 
TRAUMA
Acupuncture – atrophic round scars 
BJD 150:364, 2004
Amniocentesis dimples 
Am J Obstet Gynecol 126:247–252,
1976; JAAD 39:888–890, 1998; AD 120:1360–1362, 1984
Compression from tight fitting clothes – lipoatrophy 
JAAD
45:325–361, 2001
IVDA – skin popping 
BJD 150:1–10, 2004
Injury due to obstetric forceps or scalp electrodes
Physical trauma – atrophic nails 
Ghatan p.114, 2002,
Second Edition
Post-injection lipoatrophy 
JAAD 45:325–361, 2001
Radiation dermatitis, chronic
Scars