Paget’s disease of Bone – leg ulcer overlying focus of Paget’s
disease
AD 141:1050, 2005
Pancreatic fat necrosis
BJD 148:388–401, 2003
Paraproteinemia
Ghatan p.74, 2002, Second Edition
Porphyria cutanea tarda
BJD 148:388–401, 2003
Prolidase deficiency – autosomal recessive; skin spongy and
fragile with annular pitting and scarring; leg ulcers;
photosensitivity, telangiectasia, purpura, premature graying,
lymphedema
BJD 144:635–636, 2001; Ped Derm 13:58–60,
1996; AD 127:124–125, 1991
Protein C or S deficiency
BJD 148:388–401, 2003
Scurvy – hemorrhagic leg ulcers
Ann DV 127:510–512, 2000;
JAAD 41:895–906, 1999
Sickle cell disease – chronic leg ulcers
Clin Sci (Lond)
98:667–672, 2000; J Trop Med Hyg 85:205–208, 1982
Spherocytosis – thrombotic vasculitis
Rook p.2265, 1998,
Sixth Edition
Subcutaneous calcification (post-phlebitic subcutaneous
calcification) – chronic venous insufficiency; non-healing ulcers;
fibrosis
Radiology 74:279–281, 1960
Subcutaneous fat necrosis
TAP 1 mutation
BJD 148:388–401, 2003
NEOPLASTIC
Atrial myxoma – leg ulcers, acral red papules with claudication
JAAD 32:881–883, 1995; tender red fingertip papule JAAD
21:1080–1084, 1989
Basal cell carcinoma
JAAD 25:47–49, 1991; complicating
venous stasis ulcers
Rook p.2262, 1998, Sixth Edition;
J Derm Surg Oncol 19:150–152, 1993
Eccrine syringofibroadenoma – in a burn scar
BJD
143:591–594, 2000
Epithelioid sarcoma
BJD 118:843–844, 1988
Kaposi’s sarcoma
Rook p.2265, 1998, Sixth Edition
Leukemia – hairy cell leukemia, chronic myelogenous leukemia
South Med J 60:567–572, 1967
Lymphoma – cutaneous T-cell lymphoma
Cutis 28:43–44, 1981;
gamma/delta T-cell lymphoma with hemophagocytic syndrome
Am J Dermatopathol 16:426–433, 1994; angiocentric T-cell
lymphoma
AD 132:1105–1110, 1996; lymphomatoid
granulomatosis
AD 117:196–202, 1981; Hodgkin’s disease
BJD 148:388–401, 2003; Br J Derm 80:555–560, 1968;
subcutaneous panniculitis-like T-cell lymphoma
BJD
148:516–525, 2003; JAAD 39:721–736, 1998; cutaneous large
B-cell lymphoma
BJD 146:144–147, 2002; CD30
+
large cell
T-cell lymphoma
BJD 149:542–553, 2003; CD56
+
lymphoma
BJD 147:1017–1020, 2000
Lymphoproliferative disorder of granular lymphocytes –
ulcerated plaque
JAAD 30:339–344, 1994
Marjolin’s ulcer – squamous cell carcinoma arising in a chronic
ulcer; may present as induration and persistence of ulceration,
elevated border at edge of ulcer, breakdown of burn scar with
indurated base, nodule formation within burn scar
Rook
p.953–954, 1998, Sixth Edition; Cutis 56:168–170, 1995;
Dictionnaire de Medicine. In:Adelon N (ed.) Paris:Bechet,
1828:31–50
Melanoma
BJD 148:388–401, 2003
Metastases
BJD 148:388–401, 2003
Myelofibrosis – extramedullary hematopoiesis in myelofibrosis
JAAD 4:592–596, 1981
Neoplastic obstruction with lymphedema
Osteoclastoma
Osteosarcoma
Polycythemia vera – thrombotic vasculitis
Rook p.2265, 1998,
Sixth Edition
Porocarcinoma
BJD 152:1051–1055, 2005
Porokeratosis – congenital linear porokeratosis
Ped Derm
12:318–322, 1995
Rhabdomyosarcoma
BJD 148:388–401, 2003
Soft tissue sarcoma
BJD 148:388–401, 2003
Squamous cell carcinoma
Rook p.1689–1690, 1998,
Sixth Edition; complicating venous stasis ulcers
South Med J 58:779–781, 1965
Waldenström’s macroglobulinemia
AD 134:1127–1131, 1998;
cryoglobulin-associated ulcers
JAAD 45:S202–206, 2001
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