Schneiderman Prelims Vol-I. qxd

SCLERODERMOID CHANGES
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Schneiderman page 600-722.qxd 5/16/2006 6:51 PM Page 609

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Whistling face syndrome (craniocarpotarsal dysplasia
syndrome) 
Birth Defects 11:161–168, 1975
Winchester syndrome (hereditary contractures with
sclerodermoid changes of skin) – scleredema-like skin changes,
joint contractures, gingival hyperplasia, dwarfism, arthritis of
small joints, corneal opacities 
JAAD 50:S53–56, 2004; Am J
Med Genet 26:123–131, 1987; J Pediatr 84:701–709, 1974;
Pediatrics 47:360–369, 1971
TOXINS
Eosinophilia myalgia syndrome (
L
-tryptophan-related) –
erythematous and edematous rashes, peripheral edema,
morphea, urticaria, papular lesions; arthralgia 
BJD
127:138–146, 1992; Int J Dermatol 31:223–228, 1992; Mayo
Clin Proc 66:457–463, 1991; Ann Intern Med 112:758–762,
1990; JAMA 264:213–217, 1990
Spanish toxic oil syndrome – rapeseed oil denatured with
aniline; early see pruritic morbilliform exanthem then white,
yellow or brown papules; finally scleroderma-like syndrome
JAAD 18:313–324, 1988; JAAD 9:159–160, 1983
TRAUMA
Burns
Mechanical trauma – jackhammer, chain saw
Post-vein stripping sclerodermiform dermatitis
AD 135:1387–1391, 1999
Radiation exposure (radiation port scleroderma) – chronic
radiation dermatitis; supervoltage external beam radiation
JAAD 35:923–927, 1996; post-radiation morphea – chronic
BJD 120:831–835, 1989; postirradiation pseudosclerodermatous
panniculitis 
Ann Intern Med 142:47–55, 2005; JAAD
45:325–361, 2001; Am J Dermatopathol 23:283–287, 2001;
Mayo Clin Proc 68:122–127, 1993; radiation fibrosis JAAD
49:417–423, 2003
Spinal injury – dermal fibrosis
Surgical trauma
VASCULAR DISORDERS
Angiosarcoma of the breast post-irradiation for breast
cancer – late thickening, edema, or induration of the breast
JAAD 49:532–538, 2003
Erythrocyanosis – may have ulceration, erythema, keratosis
pilaris, desquamation, nodular lesions, edema, and fibrosis
Rook p.962–963, 1998, Sixth Edition
Lipodermatosclerosis (hypodermatitis sclerodermiformis;
sclerosing panniculitis) – chronic venous insufficiency with
hyperpigmentation, induration, inflammation; champagne bottle
legs 
JAAD 46:187–192, 2002; Rook p.2256, 1998, Sixth Edition;
Lancet ii:243–245, 1982
Lymphedema, chronic – pseudo-scleroderma; Kaposi–Stemmer
sign; failure to pick up fold of skin 
Rook p.2285, 1998, Sixth Edition
Malignant angioendotheliomatosis – scalp; livedoid red plaque
of thigh with woody induration 
Rook p.2396, 1998, Sixth Edition;
JAAD 18:407–412, 1988