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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

98
A CLINICIAN

S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Schneiderman page 1-100.qxd 5/16/2006 6:49 PM Page 98


Superficial mucocoele – oral bulla 
Rook p.3085, 1998,
Sixth Edition
Tape stripping bullae
VASCULAR
Chylous reflux 
BJD 120:695–700, 1989
Churg–Strauss disease – vesicles and bullae 
JAAD
47:209–216, 2002; Medicine 78:26–37, 1999
Edema – acute edema bullae of legs 
BJD 144:580–582, 2001
Erythema elevatum diutinum – PCT-like bullae 
BJD 124:89–91,
1991; perilesional vesicles and bullae Ann DV 104:75–76, 1977;
BJD 80:178–183, 1968
Erythromelalgia – edema and bullae of legs 
BJD 151:708–710,
2004
Henoch–Schönlein purpura 
Ped Derm 15:357–359, 1998; Ped
Derm 12:314–317, 1995
Lymphangioma circumscriptum 
BJD 83:519–527, 1970
Lymphangioma, diffuse – may or may not have widely
distributed vesicles 
Rook p.2283, 1998, Sixth Edition; BJD
134:1135–1137, 1996; AD 129:194–197, 1993
Lymphangiosarcoma (Stewart–Treves tumor) – bullae and
nodules in lymphedematous extremity 
Arch Surg 94:223–230,
1967; Cancer 1:64–81, 1948
Lymphedema, including congenital lymphedema (Milroy’s
disease); engorged dermal lymphatics mimicking appearance of
vesicles 
Rook p.2285, 1998, Sixth Edition
Polyarteritis nodosa – in children; fever, peripheral gangrene,
black necrosis, livedo reticularis, ulcers, nodules, vesiculobullous
lesions, arthralgia, nodules of face and extremities,
conjunctivitis 
JAAD 53:724–728, 2005; Ann Rheum
Dis 54:134–136, 1995
Reactive angioendotheliomatosis – red purple-purpuric patches
and plaques; includes acroangiomatosis, diffuse dermal
angiomatosis, intravascular hitiocytosis, glomeruloid
angioendotheliomatosis, angioperictomatosis (angiomatosis
with cryoproteins); associated with subacute bacterial
endocarditis, hepatitis, cholesterol emboli, arteriovenous shunt,
anti-phospholipid antibody syndrome, chronic lymphocytic
leukemia, monoclonal gammopathy, chronic renal failure,
rheumatoid arthritis 
JAAD 49:887–896, 2003
Stasis bullae
Temporal arteritis – bullae of scalp 
BJD 76:299–308, 1964
Urticarial vasculitis, including urticarial vasculitis associated with
mixed cryoglobulins, hepatitis B or C infection, IgA multiple
myeloma, infectious mononucleosis, monoclonal IgM
gammopathy (Schnitzler’s syndrome), fluoxetine ingestion,
metastatic testicular teratoma, serum sickness, Sjögren’s
syndrome, systemic lupus erythematous 
JAAD 38:899–905,
1998; Medicine 74:24–41, 1995; JAAD 26:441–448, 1992
Vasculitis – idiopathic, drug-induced 
Cutis 67:303–307, 2001;
acantholytic vesicular dermatitis with leukocytoclastic vasculitis
JAAD 15:1083–1089, 1986
Congenital Volkmann ischemic contracture (neonatal
compartment syndrome) – upper extremity circumferential
contracture from wrist to elbow; necrosis, cyanosis, edema,
eschar, bullae, purpura; irregular border with central white
ischemic tissue with formation of bullae, edema, or spotted
bluish color with necrosis, a reticulated eschar or whorled
pattern with contracture of arm; differentiate from necrotizing
fasciitis, congenital varicella, neonatal gangrene, aplasia cutis
congenital, amniotic band syndrome, subcutaneous fat
necrosis, epidermolysis bullosa 
BJD 150:357–363, 2004
Wegener’s granulomatosis 
JAAD 31:605–612, 1994

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