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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

ULCERS
655
Schneiderman page 600-722.qxd 5/16/2006 6:51 PM Page 655


Mycobacterium tuberculosis NEJM 347:1412–1418, 2002;
Ned Tidjschr Geneeskd 145:1523–1524, 2001; tuberculous
ulcer 
JAAD 19:1067–1072, 1988; chancre, primary inoculation;
scrofuloderma (ulceroglandular disease) 
JAAD 47:766–769,
2002; BJD 134:350–352, 1996; miliary tuberculosis; large crops
of vesicles, vesicles become necrotic to form ulcers 
Practitioner
222:390–393, 1979; Am J Med 56:459–505, 1974; AD
99:64–69, 1969; tuberculous gumma Cutis 66:277–279,
2000; malacoplakia of tuberculous origin – scalp ulcer
JAAD 18:577–579, 1988; erythema induratum; papulonecrotic
tuberculid 
Ped Derm 15:450–455, 1998; Ped Derm 7:191–195,
1990; ulcer of the nose Ann DV 110:731–732, 1983; phagedenic
tuberculous ulcers 
Int J Dermatol 9:283–289, 1970; lupus
vulgaris; starts as red–brown plaque; ulcerative and mutilating
forms, vegetating forms – ulcerate, areas of necrosis, invasion
of mucous membranes with destruction of cartilage (lupus vorax;
head, neck, around nose, extremities, trunk 
Int J Dermatol
26:578–581, 1987; Acta Tuberc Scand 39 (Suppl 49):1–137,
1960; eschar and ulceration JAAD 47:766–769, 2002
Mycobacterium ulcerans (Buruli ulcer) NEJM 348:1065–1066,
2003; Lancet 354:1013–1018, 1999; Med Trop (Mars) 57:83–90,
1997 (French); Med Trop (Mars) 55:363–373, 1995; Aust J
Dermatol 26:67–73, 1985; Pathology 17:594–600, 1985
Myiasis, erosive 
AD 117:59–60, 1981
Necrotizing fasciitis – painless ulcer 
Ghatan p.26, 2002,
Second Edition
Nocardiosis 
AD 130:243–248, 1994; Nocardia brasiliensis
J Inf Dis 134:286–289, 1976
North American blastomycosis 
Clin Inf Dis 22 (suppl 2)
S102–111, 1996; ulceration of the lip Rook p.3135, 1998,
Sixth Edition
Orf – eschar and ulceration 
JAAD 47:766–769, 2002
Osteomyelitis – leg ulcer overlying osteomyelitis 
Rook p.2265,
1998, Sixth Edition
Paracoccidioidomycosis – near mouth, anus, or genitalia 
J Clin
Inf Dis 23:1026–1032, 1996; ulceration of the lip Rook p.3135,
1998, Sixth Edition
Pasteurella multocida (P. haemolytica, P. pneumotropica and
P. ureae) – cellulitis with ulceration with hemorrhagic purulent
discharge with sinus tracts 
Medicine 63:133–144, 1984
Penicillium marneffei NEJM 347:1412–1418, 2002; Clin Inf Dis
18:246–247, 1994
Perirectal abscess
Phaeohyphomycosis – inoculation phaeohyphomycosis
AD 137:815–820, 2001
Plague – eschar and ulceration; ulceroglandular
JAAD 47:766–769, 2002
Portuguese man-of-war stings
Prevotella species J Clin Inf Dis (Suppl 2):S88–93, 1997
Progressive symmetric gangrene (DIC) 
Protothecosis 
JAAD 32:758–764, 1995; AD 125:1249–1252,
1989; red plaque with pustules and ulcers BJD 146:688–693,
2002
Pseudomonas – interdigital web space infection; periumbilical
pustules with necrotic ulcers; extensive necrosis in neutropenic
patients 
JAAD 11:781–786, 1984; AD 97:312–318, 1968;
Pseudomonas sepsis – bullae which rupture to yield necrotic
ulcers (ecthyma gangrenosum) – eschar and ulceration 
JAAD
47:766–769, 2002; Ped Derm 4:18–20, 1987; Medicine
64:115–133, 1985
Pyoderma
Pythiosis (
Pythium insidiosum) (alga) – cellulitis, infarcts, ulcers
JAAD 52:1062–1068, 2005
Rat bite fever – eschar and ulceration 
JAAD 47:766–769, 2002
Rickettsial pox – eschar and ulceration 
JAAD 47:766–769, 2002
Scedosporium apiospermum – ulcer of hand JAAD 39:498–500,
1998
Schistosomiasis 
Derm Clinics 17:151–185, 1999
Scopulariopsis brevicaulis
Scorpion stings 
Rook p.2265, 1998, Sixth Edition
Scrofuloderma 
Ped Derm 18:328–331, 2001
Scrub typhus – punched out ulcer with adherent crust, then
morbilliform eruption 
Clin Inf Dis 18:624, 1994; JAAD 2:359–373,
1980; eschar and ulceration JAAD 47:766–769, 2002
Serratia marcescens JAAD 25:565, 1991
Snake bites 
Rook p.2265, 1998, Sixth Edition
Sparganosis – 
Spirometra proliferum Derm Clinics 17:151–185,
1999
Spiders – necrotic arachnidism – brown recluse spider, wolf
spider, sac spider, jumping spider, fishing spider, hobo spider,
green lynx spider 
JAAD 44:561–573, 2001; Int Surg 46:24–28,
1966; eschar and ulceration JAAD 47:766–769, 2002
Sporotrichosis – finger ulcer 
Cutis 69:371–374, 2002; mimicking
pyoderma gangrenosum
NEJM 347:1412–1418, 2002; Derm
Clinics 17:151–185, 1999; AD 122:691–694, 1986
Stonefish sting
Staphylococcal adenitis – ulceroglandular disease 
JAAD
47:766–769, 2002
Streptococcal adenitis – ulceroglandular disease 
JAAD
47:766–769, 2002
Streptococcus pneumoniae Clin Inf Dis 21:697–698, 1995;
necrotizing fasciitis 
Acta Chir Belg 98:102–106, 1998; JAAD
20:774–781, 1989; Surgery 92:765–770, 1982; group B
streptococcal disease – foot ulcers, decubitus ulcers 
Clin
Inf Dis 33:556–561, 2001
Subcutaneous phaeohyphomycosis – 
Exophiala jeanselmei;
finger ulcer 
BJD 150:597–598, 2004
Syphilis – primary (chancre), secondary (noduloulcerative
syphilis, lues maligna) 
AD 113:1027–1028, 1030–1031,
1997; BJD 136:946–948, 1997; Cutis 45:119–122, 1990 ;
Jarisch–Herxheimer reaction – reactivation of primary chancre
Acta DV 76:91–92, 1996; tertiary – gumma Rook p.1251, 1998,
Sixth Edition; tabes dorsalis – painless neurotrophic ulcer of
weight bearing regions of sole 
Arch Neurol 42:606–613,
1985; syphilitic aortic aneurysm eroding through the sternum
Dur M Cardiothorac Surg 10:922–924, 1996
Tick bites – especially soft ticks 
JAAD 49:363–392, 2003
Tick typhus (Boutonneuse fever, Kenya tick typhus, African and
Indian tick typhus) (ixodid ticks) – small ulcer at site of tick bite
(tache noire) – black necrotic center with red halo; pink
morbilliform eruption of forearms, then generalizes, involving
face, palms, and soles; may be hemorrhagic; recovery
uneventful 
JAAD 2:359–373, 1980; eschar and ulceration
JAAD 47:766–769, 2002
Trichophyton rubrum in AIDS JAAD 34:1090–1091, 1996
Trichosporosis, neonatal – cellulitis evolving into necrotic ulcer
Textbook of Neonatal Dermatology, p.147, 2001
Tropical phagedenic ulcer – 
Corynebacterium pyogenes –
fusiform bacilli; eschar and ulceration 
JAAD 47:766–769, 2002
Tularemia – 
Francisella tularensis – punched-out painful ulcer
with raised ragged edges and necrotic base with regional
lymphadenopathy, lymphadenitis, or nodular lymphangitis
(ulceroglandular disease) 
JAAD 47:766–769, 2002; Clin Inf
Dis 33:573–576, 2001; Cutis 63:49–51, 1999; eschar and
ulceration; scalp ulcer with lymphadenopathy
AD 140:1531–1536, 2004
Typhoid fever 
J Trop Med Hyg 97:298–299, 1994

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