Reja I. Kirish II. Asosiy qism tetrasiklinlar guruhi preparatlari Oksitetrasiklin gidroxlorid Metasiklin gidroxlorid III. Xulosa IV. Adabiyotlar kirish

Farmakologik ta'sir

Tetratsiklin guruhidagi bakteriostatik antibiotik. Transport RNKi va ribozom o'rtasidagi murakkablikni shakllantirishni buzadi, bu protein sintezini bostirishga olib keladi. Gramatik mikroorganizmlarga qarshi faol: Staphylococcus spp. (Staphylococcus aureus, shu jumladan penitsillinaz ishlab chiqaradigan shtammlar), Streptococcus spp. , Listeria spp, Bacillus anthracis, Clostridium spp, israelii, gram-manfiy mikroorganizmlarni aktinomikoz (Streptococcus pneumoniae shu jumladan): .. Haemophilus yuqumli, Haemophilus ducreyi, Bordetella ko'kyo'tal, eng Enterobacteriaceae: Escherichia bobini, Enterobacter aerogenes jumladan Enterobacter spp, ,. Klebsiella spp., Salmonella spp., Shigella spp., Yersinia pestis, Bartonella bacilliformis, Vibrio cholerae, Vibrio fetus, Rickettsia spp., Borrelia burgdorferi, Brucella spp. (Streptomitsin bilan birgalikda), Penisillinni tayinlashga qarshi bo'lgan - Clostridium spp., Neisseria gonorrhoeae, Actinomyces spp., shuningdek, teri va inguinal limfogranuloma, Treponema spp. Mikroorganizmlar tetratsiklinga chidamli: Pseudomonas aeruginosa, Proteus spp., Serratia spp., Bacteroides spp. va A guruhining funguslari, viruslari, beta gemolitik streptokokklari (Streptococcus pyogenes strainsining 44% va Streptococcus faecalis shtammlarining 74%).