Rama Krishna Devaki

Rama Krishna Devaki

Associate Professor

Department of Biochemistry

Kamineni Institute of Medical Sciences

Sreepuram, Narketpally-508 254

Nalgonda Dt., A.P, India.

Mobile: [phone]

Tel: [phone], 272829

Fax: [phone]

Email: [e-mail]

http://www.researchgate.net/profile/Dr_Ramakrishna_Devaki/


Education

August 2002 – December 2006: Ph.D in Biochemistry at

National Institute of Mental Health & Neurosciences

Bangalore, India.

Thesis : “Effect of antidepressants on alpha1-adrenoceptors subtypes in rat brain”.
August 1995 – December 1998: M.Sc. in Medical Biochemistry

Kasturba Medical College

Manipal, India.

Thesis : “Enzyme profile in myocardial infarction”

June 1990 – July 1994: Bachelor of Science

Kakatiya University,

Khammam, India
Work experience:

27^th Dec 2010 to till today Associate Professor in Department of Biochemistry,

Kamineni Institute of Medical Sciences, Narketpally,

Nalgonda, India

28^th Dec 2006 – 27^th Dec 2010 Assistant Professor in Department of Biochemistry,

Kamineni Institute of Medical Sciences, Narketpally,

Nalgonda, India.

22^nd Jan 1999 – 4^th Sep 2002 Lecturer in Department of Biochemistry,

Kamineni Institute of Medical Sciences, Narketpally,

Nalgonda, India.
Research Experience:
August 2002 – December 2006: Ph.D in Biochemistry, NIMHANS

Advisor: Professor Dr. M. N. Subhash

August 1995 – December 1998: M.Sc. in Medical Biochemistry, MAHE

Advisor: Professor Dr. D.M. Vasudevan

Grants Sanctioned/Submitted as Project Investigator (PI):

1. Title of the Grant : “Nanoparticles: Biochemical and genetic studies for

subsequent use in humans”

Submitted to : DBT (Department of Bio- Technology) under RGYI young investigator award.
Sanctioned on : 7^th December 2010
Project Reference number: BT/PR15094/GBD/27/313/2011
Amount Sanctioned : 24,00,000=00

Grants Submitted as Co- Investigator (Co-I):
1. Title of the Grant : "Development of a Gold nanoparticle based diagnostic kit for GuillianBarre Syndrome."
Submitted to : DST (Department of Science & Technology) Nano

Mission
Project Reference Number: SR/NM/NT-1030/2011

2. Title of the Grant : “Mesenchymal stem cell separation and

characterization from birth associated tissues for

future therapy in individuals with orthopaedic

complications”.

Submitted to : DBT (Department of Bio- Technology)

Publications: 15

1. 
   Ramakrishna D and Subhash MN (2013).Effect of Amitriptyline on alpha 1-adrenergic receptors number and second messenger function on rat brain. Pakistan Journal of Biological Sciences 15(18):871-876.
   
2. 
   Afshan Rafi, Ramakrishna D, Sabitha K,Shruti Mohanty, Pragna Rao (2013). Importance of Serum copper and Vascular Endothelial Growth Factor (VEGF-A) levels in Postmenopausal bleeding. Indian Journal of Biochemistry 28(2):147-151.
   
3. 
   Ramakrishna D and Pragna Rao (2011). Nanoparticles: Is toxicity a concern?. The Journal Of The International Federation Of Clinical Chemistry And Laboratory Medicine 22 (4): 1-10.
   

4. 
   Sunethri Padma, Ramakrishna D and Jijiya Bai P (2011). Matrix Metallo Proteinases in carcinoma of Cervix - A Review. International Journal of Life Sciences and Pharma Research 1 (1): 101 – 109.
   

5. 
   Gopu Chinnapu Reddy, Ramakrishna D, Pragna Rao (2011). Sepsis is associated with iron overload in hemodialysis patients receiving intravenous iron therapy. Asian Journal of Biochemistry 6 (3): 252-262.
   

6. 
   Sunethri Padma, Ramakrishna D Jijiya Bai P and Ramana (2011). Pattern of distribution of congenital anomalies in stillborn: A hospital based prospective study. International Journal of Pharma and Bio Sciences 2(2): 604-610.
   

7. 
   Afshan Rafi, Ramakrishna D, Sabitha K, Shruti Mohanty, Pragna Rao (2011). Serum copper and Vascular Endothelial Growth Factor (VEGF-A) in Dysfunctional Uterine Bleeding. American Journal of Biochemistry and Molecular Biology 1(3):284-290.
   

8. 
   Ramakrishna D, Sumeet Roy, G.C.Reddy, Subhash, M.N (2011). Differential effect of antidepressants on Gq-protein levels in rat brain. International Journal of Pharma and Bio Sciences 2(1): 348-355.
   

9. 
   D.Ramakrishna, P.Rao (2010). Applications of G-protein coupled receptors in clinical medicine. Current Research in Neuroscience 1(1):15-23,2011.
   

10. 
    A.K. Meena, A.D. Archana, G.C.Reddy, D. Ramakrisha, Pragna Rao (2010). Antiganglioside Antibodies in Sub Types of Guillain-Barre Syndrome in an Indian Population. Journal Medical Sciences 10 (5):138-142.
    

11. 
    D.Ramakrishna, M.N.Subhash (2010). The article Differential modulation of alpha-1 adrenoceptor subtypes by antidepressants in the rat brain. Journal of Neural Transmission (2010) 117:1423-1430. DOI: 10.1007/s00702-010-0522-4
    

12. 
    D.Ramakrishna, M.N.Subhash and Sharada (2008). Differential effect of specific antidepressants on α1-adrenoceptors in rat brain. Journal of Neurochemistry 106 (supplement 1):43.
    

13. 
    D. Ramakrishna, M.N.Subhash and S. Sharada (2006). The effect of lithium on the adrenoceptors-mediated second messenger system in rat brain.
    

J. Psychiatry Neurosci. 31(4):246-252.

14. 
    M.N.Subhash and D.Ramakrishna (2006). Effect of sumatriptan on cortical 5-HT1B adrenoceptors in rat brain. Journal of Cell and Tissue Research 6(2): 743-747.
    

15. 
    D.Ramakrishna, M.N.Subhash , Sharada and Vinod (2004). Modulation of α1-adrenoceptors by tricyclic antidepressants in rat brain. Journal of Neurochemistry 88 (Issues1):77.
    

Book Chapter:

1. 
   Chapter title: “Importance of G Protein-Coupled Receptor Genetics in Clinical
   

Medicine”
Book Title: “Genetics of G Protein-Coupled Receptors-Research in the Post-

Genomic Era”
Name of the Author: Ramakrishna Devaki.
Publisher: Springer

Paper Presentations: 10

1. 
   Presented a paper entitled “Modulation of 1-adrenoceptors by tricyclic antidepressants in rat brain” Ramakrishna D, M.N.Subhash and Sharada, the 6th Biennial Meeting of the Asian-Pacific Society for Neurochemistry (APSN) held at Hong Kong, China, from 4th to 7th February 2004.
   

2. 
   Presented a paper entitled “Effect of specific antidepressants on l-adrenoceptor subtypes in rat brain” Ramakrishna D, M.N.Subhash and Sharada at Asia-Pacific Society for Neurochemistry (APSN) meeting held at Shanghai P.R. China June 23rd-26th, 2008.
   

3. 
   Presented a paper entitled “Differential Modulation of Alpha 1-adrenoceptor Subtypes by Antidepressants in the Rat Brain” Ramakrishna D et al. at World Federation of Societies of Biological Psychiatry (WFSBP) meeting held at Japan September 11th -13th, 2008.
   

4. 
   Presented a paper entitled “Effect of tricyclic antidepressants on 1-adrenoceptors rat brain” Ramakrishna D, M.N.Subhash and Sharada in Indian Association of Neurosciences-Society for Neurochemistry (IAN-SNCI) International Conference held at University of Hyderabad, Hyderabad, India, from 6th to 8th May 2004.
   

5. 
   Presented a paper entitled “Characterization of l-adrenoceptors subtypes in rat brain” Ramakrishna D, M.N.Subhash and Sharada in 31st Annual National Conference of Association of Clinical Biochemistry of India (ACBI), J.N.Medical college, Belgaum, Karnataka, India, from 1st to 4th December 2004.
   

6. 
   Presented a poster entitled “Differential effect of specific Antidepressants on l-adrenoceptors in rat brain” Ramakrishna D, M.N.Subhash and Sharada at 50th Annual Conference of theAssociation of Physiologist and Pharmacologists of India”, National Institute of Mental Health & Neurosciences, Bangalore, Karnataka, India, from 20th to 22nd December 2004 and achieved the credit of Best Poster Award.
   

7. 
   Presented a paper entitled “ Region and subtypes specific effects of SSRI and TCA drugs on 1-adrenoceptors in rat brain” Rama Krishna D, M.N.Subhash and Sharada in “ Society for Neurochemistry of India (SNCI) symposium, NCBS, Bangalore, India, from 4th to 5th, 2005.
   

8. 
   Presented a paper entitled “Effect of Lithium on α1- adrenoceptors in rat brain” Ramakrishna D and Subhash MN at International Conference on Genetic and Molecular Diagnosis in Modern Medicine held at HRD centre, Hyderabad, from 7th to 9th January, 2008.
   

9. 
   Participated in International Conference on Nano Science and Technology (ICONSAT) which was held at IIT, Mumbai, India, during February 17-20, 2010.
   

10. 
    Presented a paper entitle “Region and subtype specific effects of SSRI and TCA drugs on alpha1-adrenoceptor sub types in rat brain”. Ramakrishna D at 10^th World congress of biological psychiatry held at Prague, Czech Republic, from 29^th May to 2^nd June, 2011 and achieved the credit of Young Scientist Award.
    

Fellowships/Awards:

1. 
   Received Young Scientist Award at 10^th World congress of biological psychiatry held at Prague, Czech Republic, from 29^th May to 2^nd June, 2011.
   

2. 
   Received RGYI young investigator award from Department of Biotechnology on 7^th December 2010.
   

3. 
   Received best paper presentation award at International Asia-Pacific Society for Neurochemistry (APSN) conference 23^rd to 26^th June 2008, Shanghai, China.
   

4. 
   Professor John Miller paper presentation Award at “22nd Annual conference of Indian Academy of Neurosciences (IAN), 28th to 30^th January 2005, Belgaum, India.
   

5. 
   Received best paper presentation award at international APSN/ISN conference 4th to 8th February 2004, Hong Kong, China.
   

6. 
   Best poster presentation award at 50th Annual conference of the association of physiologist and pharmacologists of India”, National Institute of Mental Health & Neurosciences, from 20th to 22nd December 2004, Bangalore, Karnataka, India.
   

Editorial Board Member and Peer reviewer of:

1. 
   Editorial Board Member of Journal of Medical Sciences
   
2. 
   Editorial Board Member of Asian Journal of Biochemistry
   
3. 
   Editorial Board Member of Current Research in Neurosciences
   
4. 
   Research Journal of Nanoscience and Nanotechnology
   
5. 
   Editorial Board Member of American Journal of Biochemistry and Molecular Biology
   
6. 
   Advisory Editorial Board Member of International Journal of Life Sciences and Pharma Reviews.
   

Conferences and Workshops Organized:

1. 
   Executive member of “International Conference on Genetic and Molecular Diagnosis in modern Medicine” Hyderabad, February 2009.
   
2. 
   Executive member of “International Conference on Genetic and Molecular Diagnosis in modern Medicine” Hyderabad, February 2008.
   

As a External Examiner:

1. 
   External examiner in Manipal Medical College, Manipal from 2011 onwards.
   

Medical Education Training:

Undergone training in Medical Education in Kamineni Institute of Medical

Sciences on 2006.
Other Expertises:

1. 
   Empanelled As Technical Assessor for NABL from Department of Science and Technology from 2010.
   
2. 
   Achieved First class in NMR Spectroscopy certificate course from Indian Institute of Science (IISc.,) Bangalore, 2005.
   
3. 
   Achieved certificate on “Care, Breeding and Management of Laboratory Animals” from Central Animal Research Facility (CARF), during 2005-06 at NIMHANS, Bangalore, 2002.
   
4. 
   Trained at Cancer Genetics Inc. New Jersey, USA on DNA - FISH probe technology from 1^st May, 2012 to 13^th June, 2012.
   

Technical Competence

1. 
   Analytical Skills:
   
2. 
   
   

Handling, Calibration & Maintaince of Various sophicated instruments- Infra-red UV-Visible, Fluorescence spectrometer, Flourimeter, HPLC’s (UV, flouscence, IR, ELSD, Corona and Electrochemical detectors), AAS, GC-MS, LC-MS NMR (400MHz) and Tandem Mass spectroscopy (TMS). Thermal Analysers TGA, DSC and Gas Chromatography (ECD &TCD). Radio ligand binding Assay, Auto Radiography.
Nano technology Techniques:
Preparation of gold and silver nano particles, nano diagnostics, Rapid lateral flow techniques , handling of flourimetry and turbidometry techniques in identification and quantification of heavy metals. Cytotoxicity tests (MTT and MNT).
Biochemical Techniques:
Spectrophotometer, Spectrofluorometer, ELISA technique and Radio Immuno assay (β & γ Counters). Biochemical analysis using HPLC. Protein purification, Dialysis, gel filtration and HPLC purification. Dade Dimension Rxl biochemistry analyzer, Cobas Integra Biochemistry analyzer, Ilyte electrolyte analyzer, Blood Gas Analyzer, Roche e411. Immuno chemistry auto analyzer. Protein purification techniques (FPLC).
Molecular biology Techniques:
Genomic DNA extraction, Polymerase Chain Reaction (PCR), Restriction fragments length polymorphism, Agarose gel electrophoresis, and Western Blot. DNA telomerase length measurement.

Computer Skills:
Stastical Software’s: SPSS-15, Med Cal-8, Sigma Stat, Sigma plot & Origin-7.

Languages

English, Hindi, Telugu and Kannada

Professional Membership:

1. 
   Life member of “Society for Neurochemistry India” (SNCI), India.
   
2. 
   Life member of “Association of Clinical Biochemistry of India” (ACBI), India.
   
3. 
   Life member of “Indian Association of Neurosciences” (IAN), India.
   
4. 
   Life member of “Association of Pharmacological Physiological Association of India” (APPI), India.
   
5. 
   Member of International Society of Neurochemistry (ISN), c/o Kenes International
   

1-3, Rue the Chantepoulet 1211 Geneva Switzerland,Tel: [phone] Fax: [phone], Email: [e-mail]

References:

1. Dr. Rajender Babu

Director

Kamineni Institute of Medical Sciences (KIMS)

Sreepuram

Narketpally, Nalgonda.

Phone: [phone]

Email: [e-mail]

2. Dr. Pragna Rao

Professor & Head

Department of Biochemistry

Kasturba Medical College (KMC)

Manipal, Karnataka.

Phone: [phone]

Email: [e-mail], [e-mail]
3. Dr. Bindu M Kutty

Associate Professor

Department of Neurophysiology

National Institute of Mental Health & Neuro Sciences (NIMHANS),

Hosur Road, P.B. No. 2900,

Bangalore - 560 029, India.

Phone : [phone]

Email : [e-mail]

http://www.nimhans.kar.nic.in