INFILTRATIVE LESIONS
Amyloidosis – lichen amyloidosis
Rook p.2628–2630, 1998,
Sixth Edition
Colloid milium, papuloverrucous variant
BJD 143:884–887, 2000
Lichen myxedematosus – hyperkeratotic plaque
INFLAMMATORY DISEASES
Perforating folliculitis
Polymyositis – fingertip hyperkeratosis
AD 129:1207–1208, 1993
Sarcoid – keratotic spines and palmar pits
BJD 95:93–97, 1976
Toxic epidermal necrolysis – healing with verrucous hyperplasia
BJD 149:1082–1083, 2003
METABOLIC DISEASES
Acromegaly – onychauxis (hypertrophy of nail)
Ghatan p.82,
2002, Second Edition
Chronic obstructive pulmonary disease (COPD) – elbows
JAAD 13:681–682, 1985; Cutis 52:91–92, 1993
Crohn’s disease – hyperkeratotic spicules
JAAD 36:476–477,
1997
Diabetes mellitus – neuropathic hemorrhagic calluses of feet
Rook p.2675, 1998, Sixth Edition
Disseminated verruciform xanthoma
BJD 151:717–719, 2004
Dysglobulinemia – hyperkeratotic spicules
JAAD 36:476–477,
1997
Fabry’s disease – angiokeratomas
AD 140:1440–1446, 2004
Pellagra
Phrynoderma – hyperkeratotic spicules
AD 120:919–921, 1984
Renal failure, chronic – hyperkeratotic spicules
JAAD 36:476–477, 1997; uremic follicular hyperkeratosis
JAAD 26:782–783, 1992
Scurvy
Tyrosinemia type II – painful calluses
AD 130:507–512, 1994
Zinc deficiency
NEOPLASTIC DISEASES
Acantholytic acanthoma – papule or nodule
JAAD 19:783–786,
1988
Acquired digital fibrokeratoma
JAAD 12:816–821, 1985
Actinic keratoses
JAAD 37:392–394, 1997
Basal cell carcinoma – pseudohorn
Cutis 48:379, 1991
Bowen’s disease
Connective tissue nevus – mimicking linear epidermal nevus
JAAD 16:264–266, 1987
Eccrine angiomatous hamartoma
BJD 141:167–169, 1999
Eccrine syringofibroadenoma – nodule
JAAD 13:433–436, 1985
Epidermal nevus
Granular cell myoblastoma – hyperkeratotic papule; prurigo
nodularis-like lesions
Int J Derm 20:126–129, 1981
Hyperkeratotic lichen planus-like reactions combined with
infundibulocystic hyperplasia
AD 140:1262–1267, 2004
Inflammatory linear verrucous epidermal nevus – linear
dermatitic and/or psoriasiform plaques; often on leg
AD
113:767–769, 1977; AD 104:385–389, 1971
Kaposi’s sarcoma
BJD 142:501–505, 2000; hyperkeratotic
Kaposi’s sarcoma in AIDS with massive lymphedema
BJD 142:501–505, 2000
Keratoacanthoma
Large cell acanthomas – hyperkeratotic plaques
JAAD 8:840–845, 1983
Lymphoma – verrucous CTCL
Clin Exp Dermatol 21:205–208,
1996; pilotropic CTCL – keratotic spicules AD 132:683–687,
1996; Woringer–Kolopp disease – hyperkeratotic plaque
AD 120:1045–1051, 1984; follicular CTCL – follicular keratosis
JAAD 48:448–452, 2003; CTCL mimicking seborrheic keratosis
BJD 147:1264–1265, 2002
Melanocytic nevi – inflammatory nevi evolving into halo nevi in
children
BJD 152:357–360, 2005; keratotic melanocytic nevus
Int J Derm 29:713–715, 1990
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