ANTIDROMIC SENSORINEURAL FLUSHING
Auriculotemporal syndrome (Frey syndrome)
AD 133:1143–1145, 1997
Brainstem and trigeminal nerve involvement
Diabetic autonomic neuropathy
Facial migraine
Familial dysautonomia (Riley–Day syndrome)
Hyperthermia in infants
Interalia tumors of the posterior fossa
Parkinson’s disease
Spinal cord lesions
CIRCULATING VASODILATOR FLUSHING
IV contrast media (iohexol)
Adenosine 3
′
5
′
monophosphate
Aminophylline
Ghatan p.245, 2002, Second Edition
Amyl and butyl nitrite
Anti-emetics – alizapride, metoclopramide
Bromocriptine in parkinsonism
Caffeine withdrawal syndrome
Calcium channel blockers – felodipine, nifedipine, amlodipine,
diltiazem
JAAD 45:323–324, 2001; BJD 136:974–975, 1997
Carbon monoxide poisoning
Carcinoid syndrome – face, neck, upper trunk associated withs
diarrhea, breathlessness, and wheeze; foregut (stomach, lung,
pancreas, biliary tract) – bright red or pink geographic flush,
sustained, with burning, lacrimation, wheezing, sweating;
hindgut (appendix and ileum) – patchy, violaceous (cyanotic)
flush, intermixed with pallor, short duration
BJD 152:71–75,
2005; Rook p.2101, 1998, Sixth Edition; AD 77:86–90, 1958;
edema, telangiectasia, cyanotic nose and face, rosacea
Acta
DV (Stockh) 41:264–276, 1961
Chlorpropamide flush
Ann Intern Med 95:468–476, 1981
Cholinergic drugs (metrifonate)
Chylomicronemia syndrome – flushing with ingestion of alcohol
Combination anesthesia with isoflurane and fentanyl
Corticosteroids – high dose pulse methylprednisolone; oral
triamcinolone
Cyclosporine
Cyproterone
Diazoxide
Ghatan p.246, 2002, Second Edition
Etretinate
Glutamate
Ghatan p.246, 2002, Second Edition
Gonadotropin-releasing hormone therapy in patients with
prostatic cancer
J North Am Menopause Soc 2:159–161, 1995
Human corticotropin-releasing hormone
Clin Investig
72:331–336, 1994
Hydralazine
Ghatan p.246, 2002, Second Edition
Hyperbradykininism (Streeten’s syndrome)
Hyperthyroidism
IL-2 reaction
JAMA 258:1624–1629, 1987
Iohexol – radiographic contrast medium
Isosorbide dinitrate
Ghatan p.246, 2002, Second Edition
Isotretinoin
Metronidazole with or without alcohol
Mithramycin
Morphine
Nicotinamide
Nicotinic acid (high dose) (prostaglandin D
2
release)
Clin
Pharmacol Ther 50:66–70, 1991
Nifedipine
Rook p.2100, 1998, Sixth Edition
Nitrate
Ghatan p.246, 2002, Second Edition
Nitroglycerin
Rook p.2100, 1998, Sixth Edition
Opiates
Organic solvents
Papaverine
Ghatan p.246, 2002, Second Edition
Persantin
Ghatan p.246, 2002, Second Edition
Pharmacologic menopause – 4-hydroxy androsterone, danazol,
doxorubicin
AD 128:1408, 1992, tamoxifen, clomiphene citrate,
decapeptyl, leuprolide; cancer chemotherapy – doxorubicin,
alpha interferon, methramycin, cacarbazine, cisplatin
Phenolic flavanoids
Phentolamine
Rook p.2100, 1998, Sixth Edition
Pheochromocytoma
JAAD 46:161–183, 2002
Prostacycline
Circulation 106:1477–1482, 2002; Rook p.2100,
1998, Sixth Edition; NEJM 334:296–302, 1996
Prostaglandin E
Rook p.2100, 1998, Sixth Edition
Renal cell carcinoma – carcinoid-like syndrome caused by a
prostaglandin secreting renal cell carcinoma
Arch Int Med
140:1095–1096, 1980
Reserpine
Ghatan p.246, 2002, Second Edition
Rifampin
Tamoxifen
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