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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

EDEMA, HANDS AND/OR FEET
163
Schneiderman page 100-200.qxd 5/16/2006 6:49 PM Page 163


Harlequin fetus (ichthyosis congenital fetalis) – severe
non-bullous ichthyosiform erythroderma or mild erythrodermic
ichthyosis – edema of hands and feet encased in hard casts
JAAD 212:335–339, 1989; Ped Derm 6:216–221, 1989;
Int J Derm 21:347–348, 1982
Psoriatic arthritis – lymphedema of hand/forearms 
BJD
143:1297–1301, 2000; lymphedema of arms Semin Arthr
Rheum 22:350–356, 1993
Scleredema
PSYCHOCUTANEOUS DISEASES
Factitial edema of hand 
JAAD 13:988, 1985
SYNDROMES
Cardio-facio-cutaneous syndrome (NS) – xerosis/ichthyosis,
eczematous dermatitis, alopecia, growth failure, hyperkeratotic
papules, ulerythema ophryogenes, seborrheic dermatitis,
CALMs, nevi, keratosis pilaris, autosomal dominant, patchy
or widespread ichthyosiform eruption, sparse scalp hair
and eyebrows and lashes, congenital lymphedema of the
hands, redundant skin of the hands, short stature, abnormal
facies, cardiac defects 
Ped Derm 17:231–234, 2000;
JAAD 28:815–819, 1993; AD 129:46–47, 1993; JAAD
22:920–922, 1990
Carpal tunnel syndrome 
BJD 150:166–167, 2004
Chromosome 18p syndrome 
Ann Genet 31:60–64, 1988
Costello syndrome 
JAAD 32:914–7, 1995
Eosinophilic fasciitis (Shulman’s syndrome) 
BJD 100:381–384,
1979
Fibroblastic rheumatism 
Ped Derm 19:532–535, 2002
Hereditary angioedema
Kawasaki’s disease – erythema and edema of hands and feet
Am J Cardiol 83:337–339, 1999; JAAD 39:383–398, 1998
Neu–Laxova syndrome – variable presentation; mild scaling to
harlequin ichthyosis appearance; ichythosiform scaling,
increased subcutaneous fat and atrophic musculature,
generalized edema and mildly edematous feet and hands,
absent nails; microcephaly, intrauterine growth retardation,
limb contractures, low-set ears, sloping forehead, short neck;
small genitalia, eyelid and lip closures, syndactyly, cleft lip and
palate, micrognathia; autosomal recessive; uniformly fatal 
Ped
Derm 20:25–27,78–80, 2003; Curr Prob Derm 14:71–116,
2002; Clin Dysmorphol 6:323–328, 1997; Am J Med Genet
35:55–59, 1990
Neurofibromatosis – hemihypertrophy 
Rook p.2287, 1998,
Sixth Edition
Nevo syndrome 
Am J Med Genet Feb 1998
Nodules, eosinophilia, rheumatism, dermatitis, and swelling 
Clin
Exp Allergy 23:571–580, 1993
Noonan’s syndrome – transient lymphedema of hands and feet
Olmsted syndrome 
Int J Derm 36:359–360, 1997
Papular–purpuric ‘gloves and socks’ syndrome – erythema and
edema of hands and feet as initial signs 
BJD 151:201–206,
2004; JAAD 41:793–796, 1999; JAAD 37:673–705, 1997
POEMS syndrome
Reflex sympathetic dystrophy 
Cutis 68:179–182, 2001; JAAD
35:843–845, 1996; Arch Neurol 44:555–561, 1987
RS3PE remitting seronegative symmetrical synovitis with pitting
edema 
Clin Exp Rheumatol Jul-Aug:18, 2000
Secretan’s syndrome (l’oedeme bleu) 
Sly syndrome
Turner’s syndrome – congenital lymphedema of hands; resolves
in 3 years 
JAAD 46:161–183, 2002; Rook p.2283, 1998,
Sixth Edition
Translocation of chromosome 13 
Humangenetik 28:93–96, 1975
Yellow nail syndrome 
BJD 134:307–312, 1996

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