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A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1



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[Encyclopedia of Differential Diagnosis in Dermatology] Paul Schneiderman, Marc E. Grossman - A Clinician\'s Guide to Dermatologic Differential Diagnosis, Volume 1 The Text (Encyclopedia of Differential Diagnosis in D

118
A CLINICIAN’S GUIDE TO DERMATOLOGIC DIFFERENTIAL DIAGNOSIS, VOLUME 1
Schneiderman page 100-200.qxd 5/16/2006 6:49 PM Page 118


INFILTRATIVE DISEASES
Amyloidosis
Infantile systemic hyalinosis – gingival thickening
Juvenile hyaline fibromatosis – gingival thickening
Lichen myxedematosus
Plasma cell orificial mucositis (lips and tongue) 
AD
122:1321–1324, 1986
Verruciform (verrucous) xanthoma – gingiva and alveolar ridge
are most common locations 
JAAD 42:343–347, 2000; Cutis
51:369–372, 1993
Xanthoma disseminatum 
JAAD 26:433–436, 1991
INFLAMMATORY DISEASES
Cheilitis granulomatosa – cobblestoned lips
Crohn’s disease – palatal or intraoral cobblestoning or granular
appearance 
AD 135:439–442, 1999 ; nodules of gingiva JAAD
36:697–704, 1997; AD 127:887–892, 1991, JAAD 12:260–268,
1985; JAAD 27:40, 1990; cobblestoned lips Rook p.2722, 1998,
Sixth Edition
Desquamative gingivitis
Eruptive lingual papillitis – tongue papules composed of fungiform
papillae of tip and side of tongue 
BJD 150:299–303, 2004
Granular appearance 
JAAD 27:40, 1990
Migratory mucositis of the lip
Orofacial granulomatosis – facial edema with swelling of lips,
cheeks, eyelids, forehead, mucosal tags, mucosal cobblestoning,
gingivitis, oral aphthae 
BJD 143:1119–1121, 2000
Pyostomatitis vegetans – deep fissures, pustules, papillary
projections 
Oral Surg Oral Med Oral Pathol 75:220–224,
1993; J Oral Pathol Med 21:128–133, 1992; Gastroenterology
103:668–674, 1992; JAAD 21:381–387, 1989; AD 121:94–98,
1985
Sarcoidosis
Verrucous hyperplasia of the mucosa
Whipple’s disease
METABOLIC DISEASES
Pernicious anemia – cobblestoned deep red tongue 
Rook
p.2736, 1998, Sixth Edition
Plane xanthomas
Pregnancy gingivitis

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