Valieva M. Yu., senior lecturer of the department gp №1

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"Экономика и социум" №1(92) 2022 www.iupr.ru
The results of our own research.
Structural and functional parameters of the 
myocardium in patients with CVH and VCP. In patients with moderate CVH activity, 
in contrast to the indicators of healthy individuals and patients with minimal CVH 
activity, there was an increase in the size of the left, right atria, right ventricle, LV end 
diastolic volume index and LV myocardial mass index (P<0.001). In patients with 
minimal and moderate activity of CVH, a violation of the longitudinal diastolic 
function of the right ventricle and a decrease in its systolic function were found. 
(P<0.001). With minimal activity of CVH, in contrast to the control indicators, the LV 
BWW index increased, as well as the time of LV isovolumetric stress, (P<0.001). That 
is, an increase in the activity of the inflammatory process in the liver was accompanied 
by more pronounced violations of the structural and functional parameters of the heart. 
Patients with CVH and VCP did not differ in the duration of the disease, 
anthropometric indicators, and the presence of concomitant diseases in the anamnesis. 
In patients with VCP, there was an increase in the size of the left atrium by 8%, the 
LV mass index by 23%, and the rate in the descending aorta increased by 8% 
compared to the group of patients with CVI (P<0.05). Thus, in viral cirrhosis of the 
liver, more pronounced structural and functional changes of the myocardium were 
found than in CVI. Diastolic and ventricular function and LV remodeling in patients 
with CVH and VCP In all patients, the parameters of the transmitral and transtricuspid 
flows were studied during the echocardiographic study, on the basis of which the type 
of spectrum was determined for each patient: normal and pathological type of diastolic 
dysfunction (DD). The pathological type included the pseudonormal and hypertrophic 
type of DD. In patients with CVH without impaired ventricular diastolic function, the 
left atrium increased by 7% and the thickness of the interventricular septum increased 
by 12% (P<0.001). The addition of LV DD was accompanied by an increase in LV 
myocardial mass by 15%, end-diastolic LV volume by 14%, an increase in LV 
sphericity index in systole by 24% and diastole by 28%, LV shock volume by 19.6%, 

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