O`zbekiston respublikasi sog`liqni saqlash vazirligi toshkent farmasevtika instituti

Toxicity
- is the ability of chemicals substances to affect biological objects by 
causing damages
5.
Toxic substances
– in toxicology, any chemical substance which causes 
disease or death (such as intoxication, poisoning, etc.) in contact with the body 
called harmful substance (poison). 
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Toxicant
- substances which cause not only the toxicity but also provoke 
other forms of toxic processes
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Xenobiotics - 
is an alien chemicals to the body that have negative impact on 
the body despite its amount. 
8.
Poisoning - 
a pathological condition or dysfunction of biological systems 
occurring when the toxicant interacts with an organism (it is also called substance 
intoxication). 
9.
Toximeter
- a set of methods and techniques to conduct quantitative 
assessment for the toxicity and danger of harmful substances.
10.
Cumulation
- Harmful substances may gradually accumulate in the body 
with repeated interactions. This phenomenon is called cumulation or cumulation 
material occurring when proceeding substance in an organism exceeds the 
removing poison from it. 
11.
Maximum Permissible Concentration (MPC) - 
hygienic classification is 
based on quantitative assessment of danger of chemical compounds obtained on the 
basis of experimental data on the determination of their maximum permissible 
concentration. 
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Approximate Safety Level of Exposure (TSEL)
- preliminary MPC value, 
obtained by using calculation methods
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LD 50 - 
values of the statistical average lethal doses or concentrations which 
are chosen because these values corresponds to 50% death of the experimented 
objects 
14.
Drug addiction
- The World Health Organization defined drug addiction as a 
state of episodic or chronic poisoning caused by repeated introduction of the drug. 
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