Most of the readers of this book are likely to be around to experience the Singularity. As we reviewed in the previous
chapter, accelerating progress in biotechnology will enable us to reprogram our genes and metabolic processes to turn
off disease and aging processes. This progress will include rapid advances in genomics (influencing genes),
proteomics (understanding and influencing the role of proteins), gene therapy (suppressing gene expression with such
technologies as RNA interference and inserting new genes into the nucleus), rational drug design (formulating drugs
that target precise changes in disease and aging processes), and therapeutic cloning of rejuvenated (telomere-extended
and DNA-corrected) versions of our own cells, tissues, and organs, and related developments.
Biotechnology will extend biology and correct its obvious flaws. The overlapping revolution of nanotechnology
will enable us to expand beyond the severe limitations of biology. As Terry Grossman and I articulated in Fantastic
Voyage: Live Long Enough to Live Forever, we are rapidly gaining the knowledge and the tools to indefinitely
maintain and extend the "house" each of us calls his body and brain. Unfortunately the vast majority of our baby-
boomer peers are unaware of the fact that they do not have to suffer and die in the "normal" course of life, as prior
generations have done—if they take aggressive action, action that goes beyond the usual notion of a basically healthy
lifestyle (see "Resources and Contact Information," p. 489).
Historically, the only means for humans to outlive a limited biological life span has been to pass on values,
beliefs, and knowledge to future generations. We are now approaching a paradigm shift in the means we will have
available to preserve the patterns underlying our existence. Human life expectancy is itself growing steadily and will
accelerate rapidly, now that we are in the early stages of reverse engineering the information processes underlying life
and disease. Robert Freitas estimates that eliminating a specific list comprising 50 percent of medically preventable
conditions would extend human life expectancy to over 150 years.
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By preventing 90 percent of medical problems,
life expectancy grows to over five hundred years. At 99 percent, we'd be over one thousand years. We can expect that
the full realization of the biotechnology and nanotechnology revolutions will enable us to eliminate virtually all
medical causes of death. As we move toward a nonbiological existence, we will gain the means of "backing ourselves
up" (storing the key patterns underlying our knowledge, skills, and personality), thereby eliminating most causes of
death as we know it.
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