Ноябрь 2020 18-қисм

Materials and methods: 
Thirty patients aged 45 to 75 years were examined (average age 
of patients 68.2 ± 5.8 g), of which 19 are women and 11 men with arterial hypertension who 
applied to the Department of Eye Diseases, Tashkent Medical Academy for surgical treatment 
primary open-angle glaucoma. 
Inclusion criteria were patients for whom planned surgical treatment of primary angle-glaucoma 

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Ноябрь 2020 18-қисм
Тошкент
with moderately elevated and high intraocular pressure and who had arterial hypertension of 
2-3 stages and degrees, lack of previous treatment of hypertension, ineffective treatment of 
hypertension (without reaching the target numbers of blood pressure <140/90 mmHg.).
Exclusion criteria: chronic heart failure Stability 2B-3 stages, III-IV functional class; 
severe diseases of the endocrine system; chronic renal failure; dysfunction liver; angina III-
IV functional class, requiring anti arhythmics; rhythm disturbances; a history of myocardial 
infarction; symptomatic arterial hypertension. 
All patients underwent a general clinical laboratory study, including a general blood test, a 
general urine test, and a glucose test of blood, total cholesterol, low-density lipoprotein cholesterol, 
triglycerides, creatinine, urea, potassium, sodium. Blood pressure recorded by the office method 
in the patient’s position sitting after 5 min of rest. Mean blood pressure (SPBP) was calculated 
using the Hickham formula: (SBP-DBP) /three + DBP, where SBP is systolic blood pressure, 
DBP - diastolic blood pressure. Ophthalmic examination included self-refractometry, visometry, 
gonioscopy, tonometry, topography, perimetry (if necessary, computer), ophthalmoscopy direct 
and reverse. Using topography, patients were evaluated basic indicators of eye hydrodynamics 
level intraocular pressure (Po), lightness coefficient outflow (C), Becker coefficient (Po / C) 
before treatment, before surgery, after 5 days after surgical treatment. To verify changes in the 
optic nerve head, coherence tomography of the optic nerve performed, and the depth of its 
excavation was determined. 16 patients of 30 - with stage II glaucoma; 14 patients - with stage 
III glaucoma. All patients underwent NGSE (non-penetrating deep sclerectomy). Instrumental 
studies (daily monitoring of blood pressure and ECG, tonometry, tomography) were carried out 
before the appointment of preoperative therapy, through 15 days Perindopril (before surgery) 
and through 5 days after surgical treatment of glaucoma. During the operation, all patients were 
under monitoring of blood pressure. The duration of preoperative preparation was 15 days, 
postoperative follow-up - 5 days.