Article in International Journal of Current Pharmaceutical Review and Research · December 016 citations 20 reads 45,537 authors: Some of the authors of this publication are also working on these related projects

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Methods of Enzyme Immobilization
Article
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International Journal of Current Pharmaceutical Review and Research · December 2016
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Tamer M Tamer
City Of Scientific Research And Technological Applications
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Ahmed Mohamed Omer
City Of Scientific Research And Technological Applications
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Mohamed Hassan
National Research Center, Egypt
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International Journal of Current Pharmaceutical Review and Research; 7(6); 385-392 
ISSN: 0976 822X 
Review Article 
*Author for Correspondence: [e-mail]
Methods of Enzyme Immobilization 
Hassan Mohamed E
1,2*
, Tamer Tamer M
3
, Omer Ahmed M
3 
1
Chemistry of Natural and Microbial Products Department, National Research Center, El Behouth Street, Cairo 12622, 
Egypt. 
2
Center of Excellence, Encapsulation & Nanobiotechnology Group, National Research Center, El-Behouth Street, Cairo 
12622, Egypt. 
3
Polymer Materials Research Department Advanced Technologies and New Materials Research Institute (ATNMRI), 
City of Scientific Research and Technological Applications (SRTA-City), New Borg El-Arab City, P.O. Box: 21934 
Alexandria, Egypt. 
 
Available Online: 25
th
 December, 2016 
 
ABSTRACT
Enzyme immobilization is a technique specifically designed to restrict the freedom of movement of an enzyme. 
Immobilization of enzymes is a common practice, mainly in order to minimize enzyme costs on the process economics by 
making it possible to reuse the enzyme many times and also minimize the operation cost as the immobilization technique 
may be modify the enzyme behavior, thus reducing the enzyme and product costs significantly. Many techniques have 
been used previously for enzyme immobilization, as entrapment, adsorption, covalent binding, encapsulation, and cross 
linking. Here we compare and contrast the basic properties of all immobilization methods.