Māris kļaviņŠ, azamat azizov, JĀnis zaļoksnis environment, pollution, development: the case of uzbekistan



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environment-pollution-development-the-case-of-uzbekistan

Figure 6.12. 
Main 
phases of the 
development of the 
human body


6. Action of toxic substances in the environment – basic concepts of ecotoxicology 
 117
Table 6.4. 
Main substances with teratogenic effects
Substance
Effect
Metals and their compounds
Lead
Facilitates spontaneous abortion and nervous 
system disorders
Methylmercury
Teratogenic effect on the nervous system
Lithium
Teratogenic effect on the heart 
Aluminium
Teratogenic effect on the nervous system
Arsenic
Teratogenic effect
Pharmaceuticals
Diethylstilbestrol
Adenocarcinoma
Thalidomide
Teratogenic effect
Retinoids
Teratogenic effect
Chemicals
Ethyl alcohol
Intoxication of the foetus 
Chloro-organic pesticides
Facilitate spontaneous abortion
Polychlorinated biphenyls
Teratogenic effect
Ethylene oxide
Facilitates spontaneous abortion
Dioxin
Teratogenic effect
References
Information notices on diagnosis of occupational diseases. (2009) 
Luxembourg: Office for Official Publications of the European 
Communities. 
Investigating Environmental Disease Outbreaks: A Training Manual. (1991) 
Geneve: WHO.
Newman M. C. (1998) Fundamentals of Ecotoxicology. Ann Arbor Press.
Timbrell J. A. (2002) Introduction to Toxicology. 3
rd
 ed. London: Taylor and 
Francis. 
Walker C. H., Hopkin S. P., Sibly R. M., Peakall D. B. (2001) Principles of 
Ecotoxicology. 2
nd
 ed. London: Taylor and Francis. 
Wright D. A., Welbourn P. (2002) Environmental Toxicology. Cambridge: 
Cambridge University Press.
Aldridge W. N. (1996) Mechanisms and concepts in toxicology. Washington: 
Taylor and Francis.
Appraisal of tests to predict the environmental behaviour of chemicals. 
(1985) (Ed. P. Sheehan, F. Korte). Chichester: J. Wiley.
Aquatic ecotoxicology (1991) Fundamental concepts and methodologies 
(Ed. A. Boudon, F. Ribeyre), Boca Raton: CRC Press. 
Gibaldi M. (1990) Biopharmaceuticals and clinical pharmacokinetics. 
Baltimore: Williams and Wilkins. 
Handbook of environmental chemistry (Ed. O. Hutzinger) vol. 1-24  
(1980–1994), Berlin: Springer Verlag.
Lu F. (1996) Basic Toxicology. Washington: Taylor and Francis.
Moriarty F. (1999) Ecotoxicology: the study of pollutants in ecosystems. 
London: Academic Press.


118 
ENVIRONMENT, POLLUTION, DEVELOPMENT:  THE CASE OF UZBEKISTAN
Timbrell J. A. (1996) Principles of biochemical toxicology. London: Taylor 
and Francis.
Timbrell J. (2002) Introduction to toxicology. Washington: Taylor and 
Francis.
Wexler P. (1998) Encyclopedia of Toxicology. N.Y.: Academic Press.
Walker C. H., Hopkin S. P., Sibly R. M., Peakall D. B. (2001) Principles of 
ecotoxicology. Washington: Taylor and Francis.
A Small Dose of. Accessible: www.asmalldoseof.org/.
Agency for Toxic Substances. Accessible: www.atsdr.cdc.gov.
European Centre for Ecotoxicology and Toxicology of Chemicals. Accessible: 
www.ecetoc.org/.
Hazard Database. Accessible: www.evol.nw.ru/~spirov/hazard/.
Information Toxicology International. Accessible: www.infotox.com/.
Pollution Information Site. Accessible: www.scorecard.org/health-effects/.
Toxicology Source. Accessible: www.toxicologysource.com/.


7. AIR POLLUTION

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