Iii международная научно-практическая конференция

 
213 
III International Scientific and Practical Conference 
THE INCIDENCE OF TORCH (TOXOPLASMOSIS, OTHER INFECTIONS, 
RUBELLA, CYTOMEGALOVIRUS INFECTION, HERPES) - INFECTION 
AND ITS EFFECT ON THE SEVERITY OF CHRONIC LUNG DISEASE IN 
CHILDREN 
Saydalikhujaeva Sh.Kh., Rikhsikhujaev A.Kh., Matchonov D.O. 
Tashkent state dental institute 
Relevance of the study: 
In TORCH - complex include: T - toxoplasmosis, O - 
other infections, R - rubella, C - cytomegalovirus infection, H - herpes. WHO has 
recently expanded this list, add to the group of "other infection" HIV, hepatitis B and 
C, chlamydia. During pregnancy, primary infection with any of the TORCH group is 
dangerous. That is, a meeting with the infection to which immunity has not been 
developed. The presence of an infection in a pregnant woman can provoke 
termination of pregnancy at any time. It is also important to know that the risk of 
developing fetal pathology is higher in acute infection than in chronic infection. Most 
of the TORCH infections cause mild maternal morbidity, but have serious fetal 
consequences, and treatment of maternal infection frequently has no impact on fetal 
outcome. Therefore, recognition of maternal disease and fetal monitoring once 
disease is recognized are important for all clinicians. Knowledge of these diseases 
will help the clinician appropriately counsel mothers on preventive measures to avoid 
these infections, and will aid in counseling parents on the potential for adverse fetal 
outcomes when these infections are present. 
Objective: 
To analyze the incidence of chronic TORCH infection and its effect 
on the severity of chronic obstructive pulmonary disease (COPD)in childhood and 
early adolescence. 
Materials and Methods.
In pediatric pulmonology department in 1-clinic of 
Tashkent Medical Academy for the period for the period from September 2018 to 
March 2020 obtained conservative treatment 744 patients with COPD. In screening 
for TORCH-infection were analyzed using blood tests ImmunoComb for the presence 
of antibodies IgM, IgA, IgG class to the corresponding pathogen. For more accurate 
the stage of disease was analyzed paired serum. TORCH - infections identified in 46 
children, which amounted to 6.1%. Males were 28 (60.8%), female - 18 (39.2%) with 
a mean age of patients was 3 ± 1,1 year. 
Results
. In the history in 24 (57.2%) children, chronic TORCH - infection was 
detected earlier by screening study at the time of the mother's pregnancy. The 
remaining 18 chronic infections was detected for the first time. In the structure of 
TORCH - infections accounted for cytomegalovirus - 22 (47.8%), the second 
occurrence of nosology was chlamydia in 10 cases, accounting for 23.8% and 19% of 
cases, herpes simplex virus 2 (8 patients) and 6 rubella cases (14.3%). An interesting 
fact is that in patients with congenital TORCH - infection during aggravation of 
COPD, showed pronounced than in cases without concomitant TORCH - infection. 
This was expressed in a later therapeutic response to ongoing conservative therapy, as 

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