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Most common defeciency in thromboembolism



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Bog'liq
MU-MCQs-Internal-medicine (2022)

Most common defeciency in thromboembolism:

  1. Protein C

  2. Protein S

  3. Antrithrombin




INTRODUCTION — Inherited thrombophilia is a genetic tendency to venous thromboembolism. Factor V Leiden is the most common cause of the syndrome accounting for 40 to 50 percent of cases. The prothrombin gene mutation, deficiencies in protein S, protein C, and antithrombin account for most of the remaining cases, while rare causes include the dysfibrinogenemias [1,2]. The total incidence of an inherited thrombophilia in subjects with a deep vein thrombosis ranges from 24 to 37 percent overall compared with about 10 percent in controls. (See "Overview of the causes of venous
thrombosis", section on 'Inherited thrombophilia'.)




  1. Wrong about Coeliac disease:

    1. Not associated with increased malignancy




  1. While a patient was participating in medical students exam, he developed hypotension of 50/30, flushing… Treatment is:

  1. Corticosteroids

  2. Adrenaline







CUTE MANAGEMENT:




he first and most important therapy in anaphylaxis is epinephrine. There are NO absolute contraindications to pinephrine in the setting of anaphylaxis.




irway: Immediate intubation if evidence of impending airway obstruction from angioedema; delay may lead to omplete obstruction; intubation can be difficult and should be performed by the most experienced clinician available; ricothyrotomy may be necessary





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