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MU-MCQs-Internal-medicine (2022)

Wrong about hypertension:

A. Complications start >140/90 Answer: ????

  1. A diabetic patient was diagnosed with new hypertension, best management:

    1. Thiazide

    2. Enalapril

    3. Furosmide




  1. Causes of hypercalcemia, except:

    1. Cushing

    2. Thiazides



  2. All cause hyperkalemia, except:

    1. ACEI

    2. Furosemide

    3. RTA type 4



  3. The following drugs improve prognosis of patients with heart failure, except:

    1. Metoprolol

    2. ACEI

    3. Statin

    4. Fruosmide

    5. Aldosterone antagonist




Although data on diuretic efficacy are limited, a meta-analysis of a few small trials found that diuretics were
associated with reduction in mortality as well as reduced admission for worsening heart failure [25]. (See "Use of diuretics in patients with heart failure", section on 'Efficacy'.)

Statins — Clinical trials have evaluated the efficacy of statins on mortality in patients with both ischemic and nonischemic systolic HF. (See "Statin therapy in patients with heart failure".)

Summarized briefly, no benefit from statin therapy has generally been demonstrated in patients with moderate to severe heart failure due to systolic dysfunction with or without coronary artery disease. Limited data suggest that statins may benefit patients with diastolic dysfunction.



SUMMARY AND RECOMMENDATIONS — Despite strong evidence of benefit for statins in most subsets of patients with established cardiovascular disease, two large randomized trials found no benefit from initiating statin therapy in patients with symptomatic systolic heart failure (ischemic or nonischemic) and a mean left ventricular ejection fraction
≤33 percent. (See 'Statins in systolic HF' above.)


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