Ноябрь 2020 18-қисм

TREATMENT OF GLAUCOMA ON THE BACKGROUND OF APPLICATION OF 
“PERINDOPRIL”
Shofotikhov Abdulla Fatkhulla o‘g’li 
Resident of third course in ophthalmology 
department of Tashkent Medical Akademy
Telefon: [phone]
E-mail: [e-mail]
Bilalov Erkin Nazimovich 
d.m.s., professor of ophthalmology 
department of Tashkent Medical Akademy
Telefon: [phone]
E-mail: [e-mail]
Key words: 
arterial hypertension, glaucoma, preoperative preparation, tonographic indices, 
Perindopril, hydrochlorothiazide.
Summary: 
Glaucoma is one of the main causes of loss view. Surgical treatment of patients 
with primary open-angle glaucoma is the main method correction of the level of intraocular 
pressure. Medical preparation of patients who have glaucoma with arterial hypertension for 
surgical treatment remains relevant. One of the most commonly used antihypertensive medicines 
in the world is Perindopril. Nowadays evidence of proven beneficial effects of medicine allows 
applying it in a wide range of patients. Below presents the experience preparing this category 
of patients for surgery treatment of primary open-angle glaucoma in the background use of 
the medicine “Perindopril” with an assessment of the dynamics of blood pressure and eye 
hydrodynamics.
In 52 % of patients who need ophthalmic surgery treatment have Cardiovascular disease 
and in patients with glaucoma this percentage reaches 65-70%. However, advances in learning 
pathogenesis, diagnosis and treatment, glaucoma remains one of the most common reasons 
leading for blindness. According to WOH, cause of World blindness is glaucoma. It rates 
from 0.6 to 33.0%. Glaucoma blindness stays steady in rate 14-15% of the total number of all 
visually invalids In Russia. In recent years, glaucoma came to the first ranking place as ranks 
of primary visual disability ahead of cataract and traumatic damage to the organ of vision, that 
found based on widespread epidemiological studies. As a rule, patients with glaucoma belong 
to categories of the elderly (62%). Arterial hypertension (AH) is one of the determining factors 
of preoperational risk, regardless of its cause. Literature data show that risk of perioperative 
complications is minor with low blood pressure (BP). Proved that hypertension well controlled 
if treatment continues until and resumes after surgery. In patients with higher blood pressure, 
there is a greater risk of developing perioperative complications. Precisely, violations heart 
rate, myocardial infarction, hypertensive crises, circulatory failure. In case of the absence any 
compensation for blood pressure in patients operated on about glaucoma, during surgery there is 
a high risk of expulsive hemorrhage development and in postoperative period in patients of this 
group often hyphema developed, which often lead to intraocular hypertension, haemophthalmus, 
choroid detachment. Due to insufficient knowledge of this problem, it seems important to study 
the role of preoperative on one preparation of patients with arterial hypertension in glaucoma 
surgery. 
The aim of the study is to assess the dynamics of blood pressure congestion and eye 
hydrodynamics in patients with arterial hypertension during surgery treatment of primary open 
angle glaucoma against the background of the use of the drug “Perindopril”.