South Boston Scleroderma and Lupus Health Study Massachusetts Department of Public Health Bureau of Environmental Health January 2010

Table 50a: Prevalence and Incidence of SSc in South Boston versus Medical Literature

Estimate (Cases per 100,000)	Population		n	South Boston	95% Confidence Interval		Medical Literature
Prevalence^§	Overall		10	33.4	18.3	61.4	27.6 ^1
	Females	White	10	72.8	40.0	133.8	37.1 ^1
		Black	*	NC	NC	NC	43.4 ^1
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†
	Males	White	*	NC	NC	NC	7.8 ^1
		Black	*	NC	NC	NC	10.4 ^1
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†
Annual Incidence ^‡	Overall		12	1.13	0.58	1.98	0.96-1.93 ^1, 2, 3
	Females	White	12	2.27	1.18	3.98	1.28-2.7 ^1, 2
		Black	*	NC	NC	NC	3.11 ^1
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†
	Males	White	*	NC	NC	NC	0.97 ^1
		Black	*	NC	NC	NC	0.62 ^1
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†

<sup>1 Mayes 2003

2 Laing et al. 1997

3 Steen et al 1997

* n < 5

§ Point prevalence was estimated for December 31, 2000.

‡ Incidence rates were calculated for the period 1970-2000.

NC = not calculated

† Limited data available</sup>
Table 50b: Prevalence and Incidence of SLE in South Boston versus Medical Literature

Estimate (Cases per 100,000)	Population		n	South Boston	95% Confidence Interval		Medical Literature
Prevalence^§	Overall		8	26.7	13.7	52.6	14.6-149.5 ^1, 2, 3, 4
	Females	White	7	50.9	25.1	104.9	164.4-203.1^4
		Black	*	NC	NC	NC	406.3-693.7 ^4
		Asian	*	NC	NC	NC	138.7-244.5 ^4
		Hispanic	*	NC	NC	NC	92.7-103.2 ^4
	Males	White	*	NC	NC	NC	†
		Black	*	NC	NC	NC	†
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†
Annual Incidence^‡	Overall		15	1.41	0.79	2.33	1.51-5.56 ^3
	Females	White	14	2.65	1.45	4.46	1.1-3.9 ^3
		Black	*	NC	NC	NC	3.0-11.42 ^3
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†
	Males	White	*	NC	NC	NC	0.30-0.42 ^3
		Black	*	NC	NC	NC	0.8-2.50 ^3
		Asian	*	NC	NC	NC	†
		Hispanic	*	NC	NC	NC	†

<sup>1 Hochberg 1990

2 Ward 2004

3 Danchenko et al. 2006

4 Chakravarty et al. 2007

* n < 5

§ Point prevalence was estimated for December 31, 2000.

‡ Incidence rates were calculated for the period 1970-2000.

NC = not calculated

† Limited data available</sup>

1 Raynaud’s phenomenon is a vascular disorder that causes discoloration of the extremities. As upwards of 90% individuals diagnosed with SSc and SLE also suffer from Raynaud’s, it is not considered a specific disease indicator (Korn and Merkel 2005).