Dermatovenerologiya va estetik tibbiyot


prevention allergic vasculitis of skin



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Dermatologiya N3 2015

prevention allergic vasculitis of skin
TASHKENBAEVA U.A.
Tashkent medical academy
The key pathogenetic mechanism in the 
development of allergic vasculitis is an increase in 
the number of circulating immune complexes (CIC) 
is observed with a considerable quantity of antigen 
prevalence of antibodies. namely CIC and activated 
them compliments cause allergic vasculitis with 
fibrinoid nephrosis, perivascular edema, blockage of 
microcirculation, leukocyte infiltration, hemorrhage and 
degenerative changes in the lesion up to necrosis. 
Thus, prevention, improved treatment, lengthening the 
periods of remission in patients with allergic vasculitis 
is considered priority areas of medicine.
For the prevention of exacerbations and relapses 
is great importance to maintenance dispensary, 
antirecurrent interventions involving sanitation of of 
foci of chronic infection, elimination of allergenic of 
exogenous and endogenous influences. Рreventive 
measures, precluding the possibility of vasculitis 
disease include: sanitation of foci of chronic 
infections, do not allow overheating and overcooling 
of the body, avoid excessive exercise on the human 
body maintain a healthy lifestyle that excludes 
tobacco and alcohol use, hardening, improving the 
environment.
аdvisable to conduct immunological and 
biochemical examination, and it is recommended to 
conduct a study of core indicators of hemostasis in 
patients with allergic vasculitis of the skin. 
The immuno corrective necessary to carry out 
against the background of the base treatment. 
Stronger neo-C minophagen and loratal are 
possessed, antiallergic, immunocorrective and 
hepatoprotective properties.
In 92.2 % of patients with superficial and deep 
vasculitis treated with com-bined therapy, was 
received a positive therapeutic effect, allowing for 
3–4 days to reduce the length of stay in a hospital 
bed. The monitoring of patients for three years 
showed that the method of treatment would prevent 
relapses of the disease and lengthen the remission.
In order to prevent recurrence of the disease 
recommend to patients sanitation foci of chronic 
infection, adequate correction of background 
pathology.

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