Christina Prechtl Imperial College London School of Public Health 3 rd

Christina Prechtl

Imperial College London

School of Public Health

3^rd Floor ICCH Building

59/61 North Warf Road

St. Mary’s Campus/ St. Mary’s Hospital

London

W2 1LA

Email: [e-mail]

Work experience

2013 - ongoing

Imperial College London, School of Public Health, St. Mary’s Hospital

London/England

Clinical Trial Manager and Dietitian (Reg No. DT27028)

2009 - 2013

A randomized controlled trial of a duodenal sleeve bypass device (Endobarrier) compared with standard medical therapy for the management of obese subjects with type 2 diabetes

Imperial College London, Department of Investigative Medicine, Imperial Weight Centre, Charing Cross Hospital

London/England

Postdoctoral Research Fellow and Dietitian (Reg No. DT27028)

Clinical Study Co-ordinator for Phase3 Trial 20110117 testing AMG145 for reduction of LDL-Cholesterol (Amgen trial)

Clinical Study Co-ordinator for Phase3 Trial NN8022-1839 testing Liraglutide and diet counselling for weight loss (NovoNordisk trial)

Study Co-ordinator for genetic obesity study 11_LO_0935 (Personalised Medicine for Morbid Obesity)

Psychological and dietetic pre-assessments prior to bariatric surgery

Psychological and dietetic post-operative support following bariatric surgery

Lifestyle and therapy treatment for obesity

Psychological and nutritional research for obesity and before and after bariatric surgery

2006 - 2011

Imperial College London, Department of Investigative Medicine, Robert Steiner MRI Unit, Hammersmith Hospital

London/England

PhD in functional MRI of Appetite

NuSISCO project: Nutrient Sensing in Satiety Control and Obesity (Marie-Curie fellowship funded by the European Commission, in collaboration with Imperial College (London), Technical University of Munich and Unilever Food and Health Research Institute (Netherlands))

Thesis on „ Modulation of food reward systems by fasting and ghrelin: Human functional MRI studies”

Designated person of the Human Tissue Act (Record keeping of all human tissue of the Metabolic and Molecular Imaging group)

2005 - 2006
German Institute of Human Nutrition, Department of Epidemiology

Potsdam-Rehbruecke/Germany

Research Assistant

Thesis on „ Examination of incident diseases (Diabetes mellitus type 2, Cardiovascular disease and Cancer) as predictors of dietary change – analysis of prospective data of the EPIC-Potsdam cohort “

2004
Institute of Nutrition (‘Richtig Essen Institute’)

Berlin/Germany

Student internship, Nutrition counselling

2003

German Institute of Human Nutrition, Department of Epidemiology

Potsdam-Rehbruecke/Germany

Student internship, Data analysis of the EPIC-Potsdam study with main research in alcohol

2002

Institute of Health and Veterinarian, (LUA Sachsen)

Leipzig/Germany

Student internships, Microbiological, chemical and histological analysis of foods especially for milk and dairy products, meat and meat products, pastries and salads

2000 - 2005

“Friedrich-Schiller” University

Jena/Germany

Student internships, laboratory work:

Nutritional Toxikology, Food Technology, Nutrional Physiology, Human Nutrition, Food Chemistry, Biochemistry, Chemistry (Organic and Anorganic), Molecular Biology, Microbiology, Zoology, Botany, Physics

Education

2011 - 2013

Sheffield Hallam University

Ascott/ UK

Practitioner Training in Cognitive Analytical Therapy (CAT), PgD

2006 - 2010

Imperial College London

London/ UK

PhD in functional MRI of Appetite

2002 - 2006

University of Jena “Friedrich-Schiller”

Jena/Germany

Study in Dietetics, MSc

2000 - 2002

University of Jena “Friedrich-Schiller”

Jena/Germany

Study in Dietetics, BSc

2002 - 2003

University of Madrid “Complutense”

Madrid/Spain

Study in Biology, exchange year

2000

Collège International de Cannes

Cannes/France

Study in French, exchange year, DELF (Diplome d’Études en Langue Francaise)

1999

Language school of Nimes “Vivent les Langues”

Nimes/France

Study in French, exchange year

1994 - 1999

Grammar school “Platanengymnasium”

Altenburg/Germany

“Abitur” (german general certificate of education – GCE/ A-levels)

Additional Information
Computing

MS Word, Excel, Access, Power Point, Endnote, SAS, SPSS, Sigma Stat, Internet, Linux, FSL, SPM5, ADI Instruments, InForm EDC

Languages

Fluently written and spoken German, English, Spanish and French

Courses, Workshops 2006-2013

Inform Data Checker Training

Inform User Acceptance Testing

Clinical Trial electronic data capturing course: “Inform system”

Clinphone RTSM (Randomisation and Trial Supply Management)

Phlebotomy (venepuncture and cannulation) 2011/2012

Good Clinical Practice February 2013

Clinical Research Associate (CRA) Training September 2013

Ethics workshop

Human Tissue Act workshop

Consent form and participant information sheet workshop

InForm level 2 training (research data management system)

Personal license for the use of animals in scientific procedures ICL

FSL course Brisbane / Australia

MRI physics

FMRI methodology for pharmaceutical research workshop

ADI Instruments Labchart

Statisitics and SPSS

PhD personal skills courses (applied writing, communication and presentation, poster presentation, perfecting literature review, writing for publications, critical appraisal of literature, preparaing for leadership)

Conferences

NUGO 2008 Potsdam/Germany

ASO 2009 Managing Appetite London/ UK

ISMRM 2009 17^th Sceintific meeing Honolulu/Hawaii

The Rank Prize Funds 2009, Mini-symposium on Regulation of Appetite Grasmere/UK

ICO 2010, Stockholm/Sweden

ECO 2011, Istanbul/Turkey
Memerships

Association for Cognitive Analytic Therapy (ACAT)

Health and Care and Professions Council (Reg No. DT27028)
Referee details available upon request

Abstracts, Publications, Reviews, Public Engagements
2008 Oral Communications

Increased desire for food when fasted is associated with increased fMRI activation in the ventral striatum, insula and amygdala

A.P.Goldstone, C.G. Prechtl de Hernandez, J.D. Beaver, K.Muhammed, G.Bell, G.Durighel, E.Hughes, A.D.Waldman & J.D.Bell

ISMRM 16th Scientific Meeting, Toronto, Canada, May 2008

ISMRM Proceedings 100, 2008
2008 Posters

Increased desire for food when fasted is associated with increased activation of the ventral striatum, insula and amygdala in humans

A.P.Goldstone, C.G. Prechtl de Hernandez, J.D. Beaver, K. Muhammed, G.Bell, G.Durighel, E.Hughes, A.D.Waldman & J.D.Bell

British Endocrine Society, Harrogate April 2008
Fasting Biases Brain Reward Systems Towards High-Calorie Foods

A. P. Goldstone, C. G. Prechtl de Hernandez, J. D. Beaver, C. Croese, K. Muhammed G. Bell, G. Durighe, E. Hughes, A. D. Waldman, G. Frost & J. D. Bell

British Endocrine Society, Washington DC, USA, 10-13 June 2009
2008 Posters (3^rd communication prize)

Skipping breakfast biases brain reward systems towards high-calorie foods

C.G. Prechtl de Hernandez, J.D. Beaver, K. Muhammed, G.Bell, G.Durighel, E.Hughes, A.D.Waldman, J.D.Bell & A.P.Goldstone

NuGOWeek 2008, 5^th annual conference meeting, Potsdam, Germany, September 2008
2009 Electronic Posters

Reward Sensitivity and Positive Affect Influence Brain Activation to Food Pictures of Different Caloric Value

C.G. Prechtl de Hernandez, J.D. Beaver, C. Croese, K. Muhammed, G. Bell1, G. Durighel, E. Hughes, A.D. Waldman, G. Frost, J.D. Bell1 & A.P. Goldstone

ISMRM 17th Scientific Meeting, , Honolulu, Hawai'i, USA. 18 - 24 April 2009
2009 Oral Communication

Dietary Restraint Influence Brain Activation to Food Pictures of Different Caloric Value

C.G. Prechtl de Hernandez, J.D. Beaver, C. Croese, K. Muhammed, G. Bell1, G. Durighel, E. Hughes, A.D. Waldman, G. Frost, J.D. Bell1, and A.P. Goldstone

The Rank Prize Fund, Mini-symposium on Regulation of Appetite, , Grasmere,UK. 13- 16 June 2009
2009 Publications

Fasting Biases Brain Reward Systems Towards High-Calorie Foods

A. P. Goldstone, C. G. Prechtl de Hernandez, J. D. Beaver, C. Croese, K. Muhammed G. Bell, G. Durighe, E. Hughes, A. D. Waldman, G. Frost & J. D. Bell

European Journal of Neuroscience 2009, 30(8):1625-35
2009 Posters

Dietary Restraint Influence Brain Activation to Food Pictures of Different Caloric Value

C.G. Prechtl de Hernandez, J.D. Beaver, C. Croese, K. Muhammed, G. Bell1, G. Durighel, E. Hughes, A.D. Waldman, G. Frost, J.D. Bell1, and A.P. Goldstone

MRC CSC Retreat and Neuroscience Technology symposium South Kensington, London, UK. 7^th October 2009

2010 Oral Communication

Ghrelin Mimics Fasting in Biasing Food Appeal towards High-Calorie Foods.

A.P. Goldstone, C.G. Prechtl de Hernandez, S. Scholtz, G. Durighel, S.S. Deliran, T. Wong, D. Ashby, G. Frost, SR Bloom, JD Bell

American Endocrine Scociety, San Diego, USA, 19-22 June 2010
2010 Posters

Individual Diffrences in Dietary Restraint Predicts Neural Responses in Executive Control and Affective Reward Systems to High-Calorie Foods.

C.G. Prechtl de Hernandez, J.D. Beaver, C. Croese, K. Muhammed, G. Bell, G. Durighel, E. Hughes, A.D. Waldman, S. Scholtz, N.S. Chhina, G. Frost, J.D. Bell, and A.P. Goldstone

International Congress of Obesity, Stockholm, Schweden, 11-15 July 2010
Ghrelin Mimics Fasting in Biasing Food Appeal towards High-Calorie Foods.

A.P. Goldstone, C.G. Prechtl de Hernandez, S. Scholtz, G. Durighel, S.S. Deliran, T. Wong, D. Ashby, G. Frost, SR Bloom, J.D. Bell

International Congress of Obesity, Stockholm, Schweden, 11-15 July 2010
Gastric Bypass Surgery Has Beneficial Effects on Eating Behaviour and Mood.

S. Scholtz, C.W. leRoux, C.G. Prechtl de Hernandez, S. Deliran, A. Ahmed, A.P. J.D. Bell, and A.P. Goldstone.

International Congress of Obesity, Stockholm, Schweden, 11-15 July 2010
2010 Prizes

Tackling Obesity? We need to use our brain!

C.G. Prechtl de Hernandez

Postgraduate Essay Highly Commended Certificate

Society for Endocrinology, December 2010
2011 Posters

Insula and orbitofrontal cortex activation to food stimuli predicts human food intake

C.G. Prechtl de Hernandez, S. Scholtz, N.S. Chhina, G. Durighel, T. Wong, G. Frost, J.D. Bell and A.P. Goldstone

European Congress of Obesity, Istanbul, Turkey, 25-28 May 2011
2012 Posters

Salience Resting State Network Integrity is Increased in Obesity and Predicts Orbitofrontal Cortex Activation to High-Calorie Food Cues

Starke JA, Anjari MA, Prechtl CG, Scholtz S, Miras A, Chhina N, Sleeth M, Daud NM, Ismail NA, Durighel G, Leech R, Sharp DJ, Frost GS, Bell JD & Goldstone AP

Obesity Society, San Antonio, Texas USA, Sept 2012
Salience Resting State Network Integrity in the Orbitofrontal Cortex Predicts Task Activation to Viewing High-Calorie Foods when Fasted

A.P.Goldstone, C.G. Prechtl, J.A. Starke, S. Scholtz, N. Chhina, A. Miras, G. Durighel, R. Leech, D.J. Sharp, C. Beckmann, G.S Frost & J.D. Bell

Submitted to Society of Neuroscience, New Orleans, USA, October 2012
Lack of Modulation of Brain Resting State Networks by Fasting and Ghrelin in Humans

J.A. Starke, C.G. Prechtl, S. Scholtz, N. Chhina, A. Miras, G. Durighel, R. Leech, D.J. Sharp, C. Beckmann, G.S Frost, S.R. Bloom, J.D. Bell & A.P.Goldstone

Submitted to Society of Neuroscience, New Orleans, USA, October 2012
2013 Posters

Salience resting state network integrity is increased in obesity and predicts orbitofrontal cortex activation to high-calorie food cues

Starke JA, Anjari MA, Prechtl CG, Scholtz S, Miras AD, Chhina N, Durighel G, Sleeth ML, Frost GS, Bell JD & Goldstone AP

Obesity Society, Atlanta, USA, Nov 2013
2013 Publications

Preoperative exposure to a high-fat vs. a low-fat diet does not influence weight loss after gastric bypass surgery, but does affect patterns of food selection.

F Seyfried, AD Miras, M Bueter, C G Prechtl, AC Spector, CW le Roux

Surg Endosc May 2013
2014 Publications

Obese patients after gastric bypass surgery have lower brain-hedonic responses to food than after gastric banding

Samantha Scholtz, Alexander D Miras , Navpreet Chhina, Christina G Prechtl,

Michelle L Sleeth, Norlida M Daud, Nurhafzan A Ismail, Giuliana Durighel, Ahmed R Ahmed, Torsten Olbers, Royce P Vincent, Jamshid AlaghbandNZadeh, Mohammad A Ghatei, Adam D Waldman, Gary S Frost, Jimmy D Bell, Carel W le Roux, Anthony P Goldstone

Gut June 2014
Ghrelin mimics fasting to enhance human hedonic, orbitofrontal cortex and hippocampal responses to food

Goldstone AP, Prechtl CG, Scholtz S, Miras AD, Chhina N, Durighel G, Deliran SS, Beckmann C, Ghatei MA, Ashby DR, Waldman AD, Gaylinn BD, Thorner MO, Frost GS, Bloom SR, Bell JD

American Journal of Clinical Nutrition April 2014

Annie Bell’s Low Carb Revolution

Annie Bell and Alexander D. Miras (Christina G. Prechtl in preface of book)

Kyle Books January 2014 (ISBN-10:0857831828)
Psychological characteristics, eating behaviour and quality of life assessment of obese patients undergoing weight loss interventions

Alexander D. Miras, Werd Al-Najim, Sabrina N. Jackson, Jenny McGirr, George Tharakan, Lisa Cotter, Carel W. le Roux, Christina G. Prechtl and Samantha Scholtz

Scandinavian Journal of Surgery July 2014

Reviewer for Journals
2011 Manuscript for Clinical Obesity

A Randomized Trial of a Brief Intervention for Obesity in

College Students

Buscemi J., Yurasek, A., Dennhardt, A., Martens, M., Murphy, J.

2013 Manuscript for Clinical Obesity

Exploring uncertainty in adolescent bariatric teams: an interpretative phenomenological analysis.

Doyle, Colville, S., Brown, P., Christie, D.
2013 Manuscript for Clinical Obesity

The Effectiveness of Including Support People in a Cognitive Behavioural Weight Loss Maintenance Program for Obese Adults: Study Rationale and Design

Rieger, E., Treasure, J., Swinbourne, J., Adam, B., Manns, C., Caterson, I.


Public Engagement
2013 Television

Researcher and Dietetic Therapist on Weight Loss Programme

“The Fat Family Tree”

Broadcasted on 23rd May 2013 on Channel 4

18^th August 2013