Albinism is caused by melanin production defect. Albinism, a clinically and genetically heterogeneous group of diseases, is developed as a result of genetic defects in the process of normal melaninogenesis


Albinism type IV with a moderate decrease in pigment content



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chemistry

Albinism type IV with a moderate decrease in pigment content: The type of inheritance is AR. There is tyrosinase in the hair bulbs.
Clinic: nystagmus, 50% of patients with strabismus; sun sensitivity is not full-brown.
Ocular albinism: The type of inheritance is AR. Photophobia, nystagmus, translucent iris, decreased visual acuity, refractive errors, strabismus, fundus changes typical for albinism.
Ocular albinism, sex-linked: The type of inheritance is recessive, X-linked. Occurs only in males; fundus changes, which are typical for albinism, are revealed in female carriers.
Clinic: similar to an autosomal recessive form of ocular albinism.

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